Porcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets

Abstract Rotavirus (RV) is considered a major cause of acute viral gastroenteritis in young animals. RV is classified into nine species, five of which have been identified in pigs. Most studies worldwide have highlighted diarrhoea outbreaks caused by RVA, which is considered the most important RV sp...

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Autores principales:	Flavia Megumi Miyabe, Alais Maria Dall Agnol, Raquel Arruda Leme, Thalita Evani Silva Oliveira, Selwyn Arlington Headley, Thiago Fernandes, Admilton Gonçalves de Oliveira, Alice Fernandes Alfieri, Amauri Alcindo Alfieri
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/11571963e017486b9b1755552a859fd3
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spelling	oai:doaj.org-article:11571963e017486b9b1755552a859fd32021-12-02T13:34:00ZPorcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets10.1038/s41598-020-78797-y2045-2322https://doaj.org/article/11571963e017486b9b1755552a859fd32020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78797-yhttps://doaj.org/toc/2045-2322Abstract Rotavirus (RV) is considered a major cause of acute viral gastroenteritis in young animals. RV is classified into nine species, five of which have been identified in pigs. Most studies worldwide have highlighted diarrhoea outbreaks caused by RVA, which is considered the most important RV species. In the present study, we described the detection and characterization of porcine RVB as a primary causative agent of diarrhoea outbreaks in pig herds in Brazil. The study showed a high frequency (64/90; 71.1%) of RVB diagnosis in newborn piglets associated with marked histopathological lesions in the small intestines. Phylogenetic analysis of the VP7 gene of wild-type RVB strains revealed a high diversity of G genotypes circulating in one geographic region of Brazil. Our findings suggest that RVB may be considered an important primary enteric pathogen in piglets and should be included in the routine differential diagnosis of enteric diseases in piglets.Flavia Megumi MiyabeAlais Maria Dall AgnolRaquel Arruda LemeThalita Evani Silva OliveiraSelwyn Arlington HeadleyThiago FernandesAdmilton Gonçalves de OliveiraAlice Fernandes AlfieriAmauri Alcindo AlfieriNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Flavia Megumi Miyabe Alais Maria Dall Agnol Raquel Arruda Leme Thalita Evani Silva Oliveira Selwyn Arlington Headley Thiago Fernandes Admilton Gonçalves de Oliveira Alice Fernandes Alfieri Amauri Alcindo Alfieri Porcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets
description	Abstract Rotavirus (RV) is considered a major cause of acute viral gastroenteritis in young animals. RV is classified into nine species, five of which have been identified in pigs. Most studies worldwide have highlighted diarrhoea outbreaks caused by RVA, which is considered the most important RV species. In the present study, we described the detection and characterization of porcine RVB as a primary causative agent of diarrhoea outbreaks in pig herds in Brazil. The study showed a high frequency (64/90; 71.1%) of RVB diagnosis in newborn piglets associated with marked histopathological lesions in the small intestines. Phylogenetic analysis of the VP7 gene of wild-type RVB strains revealed a high diversity of G genotypes circulating in one geographic region of Brazil. Our findings suggest that RVB may be considered an important primary enteric pathogen in piglets and should be included in the routine differential diagnosis of enteric diseases in piglets.
format	article
author	Flavia Megumi Miyabe Alais Maria Dall Agnol Raquel Arruda Leme Thalita Evani Silva Oliveira Selwyn Arlington Headley Thiago Fernandes Admilton Gonçalves de Oliveira Alice Fernandes Alfieri Amauri Alcindo Alfieri
author_facet	Flavia Megumi Miyabe Alais Maria Dall Agnol Raquel Arruda Leme Thalita Evani Silva Oliveira Selwyn Arlington Headley Thiago Fernandes Admilton Gonçalves de Oliveira Alice Fernandes Alfieri Amauri Alcindo Alfieri
author_sort	Flavia Megumi Miyabe
title	Porcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets
title_short	Porcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets
title_full	Porcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets
title_fullStr	Porcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets
title_full_unstemmed	Porcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets
title_sort	porcine rotavirus b as primary causative agent of diarrhea outbreaks in newborn piglets
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/11571963e017486b9b1755552a859fd3
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Porcine rotavirus B as primary causative agent of diarrhea outbreaks in newborn piglets

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