UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma

UTX is a tumor suppressor gene located on the X-chromosome so it could potentially contribute to the cancer gender bias. Here the authors, using a mouse model of B cell lymphoma, show that UTX is a dosage sensitive tumor suppressor and may be responsible for some of the increased incidence and possi...

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Bibliographic Details
Main Authors: Xiaoxi Li, Yanli Zhang, Liting Zheng, Mingxian Liu, Charlie Degui Chen, Hai Jiang
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/115f883b4a904c84bf10f1d3aaa7d72c
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