Assessment of complications due to intratympanic injections

Objective: The purpose of the study is to report and to analyze the complications following intratympanic injections (ITI) of steroids. The occurrence rate of complications at different ITI sites, four quadrants of eardrum, was also compared. Methods: A retrospective clinical review in a medical cen...

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Autores principales:	Yu-Chuan Liu, Fan-Hsiang Chi, Ting-Hua Yang, Tien-Chen Liu
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2016
Materias:	Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/116948afadd64285b32e0cb4d4feeed5
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spelling	oai:doaj.org-article:116948afadd64285b32e0cb4d4feeed52021-12-02T12:57:43ZAssessment of complications due to intratympanic injections2095-881110.1016/j.wjorl.2015.11.001https://doaj.org/article/116948afadd64285b32e0cb4d4feeed52016-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881115300172https://doaj.org/toc/2095-8811Objective: The purpose of the study is to report and to analyze the complications following intratympanic injections (ITI) of steroids. The occurrence rate of complications at different ITI sites, four quadrants of eardrum, was also compared. Methods: A retrospective clinical review in a medical center. Each patient received ITI twice in a week for 2â3 consecutive weeks as a salvage therapy for sudden sensorineural hearing loss. Post-injection complications, especially transient dizziness and vertigo, were recorded. Patients with acute or chronic vertigo episodes in 1 month were excluded. Results: A total of 59 patients with sudden sensorineural hearing loss and a total of 278 times of ITI were performed in 1 year. The post-injection complications included pain, tongue numbness, transient dizziness, vertigo, tinnitus, and a small persistent perforation. There was no significant difference in the occurrence of these complications between the injections sites on the 4 quadrants of the tympanic membrane. However, there was statistical significance in the post-injection vertiginous episode after IT injections to posterior-inferior quadrant (Q3) and posterior-superior quadrant (Q4) compared to anterior-superior quadrant (Q1) and anterior-inferior quadrant (Q2) (PÂ =Â 0.0113). Conclusion: IT injection is recommended to be applied to the Q2 since the Q1 and Q4 injections are more likely to induce the adverse effect of tongue numbness, while the Q3 and Q4 areas are more likely to induce post-injection vertigo. Keywords: Intratympanic injection, Sudden deafness, Complications, VertigoYu-Chuan LiuFan-Hsiang ChiTing-Hua YangTien-Chen LiuKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 2, Iss 1, Pp 13-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Otorhinolaryngology RF1-547 Surgery RD1-811 Yu-Chuan Liu Fan-Hsiang Chi Ting-Hua Yang Tien-Chen Liu Assessment of complications due to intratympanic injections
description	Objective: The purpose of the study is to report and to analyze the complications following intratympanic injections (ITI) of steroids. The occurrence rate of complications at different ITI sites, four quadrants of eardrum, was also compared. Methods: A retrospective clinical review in a medical center. Each patient received ITI twice in a week for 2â3 consecutive weeks as a salvage therapy for sudden sensorineural hearing loss. Post-injection complications, especially transient dizziness and vertigo, were recorded. Patients with acute or chronic vertigo episodes in 1 month were excluded. Results: A total of 59 patients with sudden sensorineural hearing loss and a total of 278 times of ITI were performed in 1 year. The post-injection complications included pain, tongue numbness, transient dizziness, vertigo, tinnitus, and a small persistent perforation. There was no significant difference in the occurrence of these complications between the injections sites on the 4 quadrants of the tympanic membrane. However, there was statistical significance in the post-injection vertiginous episode after IT injections to posterior-inferior quadrant (Q3) and posterior-superior quadrant (Q4) compared to anterior-superior quadrant (Q1) and anterior-inferior quadrant (Q2) (PÂ =Â 0.0113). Conclusion: IT injection is recommended to be applied to the Q2 since the Q1 and Q4 injections are more likely to induce the adverse effect of tongue numbness, while the Q3 and Q4 areas are more likely to induce post-injection vertigo. Keywords: Intratympanic injection, Sudden deafness, Complications, Vertigo
format	article
author	Yu-Chuan Liu Fan-Hsiang Chi Ting-Hua Yang Tien-Chen Liu
author_facet	Yu-Chuan Liu Fan-Hsiang Chi Ting-Hua Yang Tien-Chen Liu
author_sort	Yu-Chuan Liu
title	Assessment of complications due to intratympanic injections
title_short	Assessment of complications due to intratympanic injections
title_full	Assessment of complications due to intratympanic injections
title_fullStr	Assessment of complications due to intratympanic injections
title_full_unstemmed	Assessment of complications due to intratympanic injections
title_sort	assessment of complications due to intratympanic injections
publisher	KeAi Communications Co., Ltd.
publishDate	2016
url	https://doaj.org/article/116948afadd64285b32e0cb4d4feeed5
work_keys_str_mv	AT yuchuanliu assessmentofcomplicationsduetointratympanicinjections AT fanhsiangchi assessmentofcomplicationsduetointratympanicinjections AT tinghuayang assessmentofcomplicationsduetointratympanicinjections AT tienchenliu assessmentofcomplicationsduetointratympanicinjections
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Assessment of complications due to intratympanic injections

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