Two independent positive feedbacks and bistability in the Bcl-2 apoptotic switch.
<h4>Background</h4>The complex interplay between B-cell lymphoma 2 (Bcl-2) family proteins constitutes a crucial checkpoint in apoptosis. Its detailed molecular mechanism remains controversial. Our former modeling studies have selected the 'Direct Activation Model' as a better...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2008
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Acceso en línea: | https://doaj.org/article/117c13c06f364478a72127ca88545c10 |
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