Morphological predictors for microsatellite instability in urothelial carcinoma

Abstract Introduction Microsatellite instability occurs due to a series of mutations in the DNA pairing error repair (Mismatch repair; MMR) genes, which can affect germ cells as occurs in Lynch syndrome, whose patients are at high risk of developing multiple cancers. The loss of MMR protein is commo...

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Autores principales: Eduardo Sobrino-Reig, Telma Meizoso, Jesús García, David Varillas-Delgado, Yasmina B. Martin
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/118057f17c734cdd8ee5a47fa694aea4
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