Bactobilia Among Patients with Uncomplicated Cholelithiasis Undergoing Laparoscopic Cholecystectomy: The Risk Factors and Effects on Postoperative Infectious Complications

Background: Determining the rate of bactibilia among patients under going laparoscopic cholecystectomy (LC) and its correlationswith predisposing factors and postoperative infections, which help evaluate the need for prophylactic antibiotic.Methods: In this prospective study, 85 consecutive patients...

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Autores principales: Leila Ghahramani, Marzie Rezaeian Jahromi, Gholamreza Pouladfar, Alimohammad Bananzadeh, Alireza Safarpour, Seyed Vahid Hosseini, Manli Aminshahidi
Formato: article
Lenguaje:EN
Publicado: Shiraz University of Medical Sciences 2017
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Acceso en línea:https://doaj.org/article/1192e5fb3a68472aac13c2588758cac9
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Sumario:Background: Determining the rate of bactibilia among patients under going laparoscopic cholecystectomy (LC) and its correlationswith predisposing factors and postoperative infections, which help evaluate the need for prophylactic antibiotic.Methods: In this prospective study, 85 consecutive patients with uncomplicated cholelithiasis who underwent LC were enrolledfrom 2012 to 2013. Routine bile culture wasdoneat the time of LC. Patients were divided into 2 groups, 1 with negative bile cultureandanother with bactibilia. Demographic and laboratory data were compared. Patients were followedup10 days after their laparoscopyand 1 month after discharge to monitor the presence of infection.Results: A total of 7 cultures of bile were positive for bacteria (8.2 %). The patients’ age was the sole factor with a significant relationshipwith the rate of bactobilia (P = 0.016). Within 10 days after surgery, fever and surgical site infection were detected in 10.6% ofpatients, which was not significantly different in the 2 groups. There were no complications in the 30-day follow-up.Conclusions: Detecting bactobilia with low frequency and the lack of correlation between bactobilia and postoperative infectious,complications did not support prescribing prophylactic antibiotic in respective patients. The older age was the sole predisposingfactor for the development of bactobilia.