Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants

The role played by human protein TLR2 in inflammation and sepsis varies for different bacterial pathogens. Here, Hanzelmann et al. show that the differential abilities of Staphylococcus aureusstrains to activate TLR2 depend on their production of peptides that release lipoproteins known to act as TL...

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Autores principales: Dennis Hanzelmann, Hwang-Soo Joo, Mirita Franz-Wachtel, Tobias Hertlein, Stefan Stevanovic, Boris Macek, Christiane Wolz, Friedrich Götz, Michael Otto, Dorothee Kretschmer, Andreas Peschel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1193e0fa2ae749c19e681f02dac202f8
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