Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation

ORAI3 is part of pore forming calcium channels involved in T cell activation. Here the authors show that there is increased expression of ORAI3 in T cells from patients with rheumatoid arthritis and that the transcription factor IKAROS negatively regulates the ORAI3 promoter, indicating a regulatory...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhongde Ye, Yi Shen, Ke Jin, Jingtao Qiu, Bin Hu, Rohit R. Jadhav, Khushboo Sheth, Cornelia M. Weyand, Jörg J. Goronzy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/1194013638654e75b64350cd53e610e5
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares