Dengue virus targets the adaptor protein MITA to subvert host innate immunity.

Dengue is one of the most important arboviral diseases caused by infection of four serotypes of dengue virus (DEN). We found that activation of interferon regulatory factor 3 (IRF3) triggered by viral infection and by foreign DNA and RNA stimulation was blocked by DEN-encoded NS2B3 through a proteas...

Full description

Saved in:
Bibliographic Details
Main Authors: Chia-Yi Yu, Tsung-Hsien Chang, Jian-Jong Liang, Ruei-Lin Chiang, Yi-Ling Lee, Ching-Len Liao, Yi-Ling Lin
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Online Access:https://doaj.org/article/11abf349e5af46ddb7c9fe19efa607d3
Tags: Add Tag
No Tags, Be the first to tag this record!