A general pharmacodynamic interaction model identifies perpetrators and victims in drug interactions

Assessment of pharmacodynamic interactions is at the heart of combination therapy development. Here the authors introduce a general drug interaction scoring model that enables quantification of synergistic and antagonistic interactions and determination of the directionality of the interactions.

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Autores principales: Sebastian G. Wicha, Chunli Chen, Oskar Clewe, Ulrika S. H. Simonsson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/11acac90593d417596ce8ff040aeaa85
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