A general pharmacodynamic interaction model identifies perpetrators and victims in drug interactions
Assessment of pharmacodynamic interactions is at the heart of combination therapy development. Here the authors introduce a general drug interaction scoring model that enables quantification of synergistic and antagonistic interactions and determination of the directionality of the interactions.
Guardado en:
Autores principales: | Sebastian G. Wicha, Chunli Chen, Oskar Clewe, Ulrika S. H. Simonsson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/11acac90593d417596ce8ff040aeaa85 |
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