Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway
IgG glycosylation is an important factor in immune function, yet the molecular details of protein glycosylation remain poorly understood. The data-driven approach presented here uses large-scale plasma IgG mass spectrometry measurements to infer new biochemical reactions in the glycosylation pathway...
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Nature Portfolio
2017
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oai:doaj.org-article:11aecacd968d49ca905c6b1672c3015d2021-12-02T17:06:12ZNetwork inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway10.1038/s41467-017-01525-02041-1723https://doaj.org/article/11aecacd968d49ca905c6b1672c3015d2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01525-0https://doaj.org/toc/2041-1723IgG glycosylation is an important factor in immune function, yet the molecular details of protein glycosylation remain poorly understood. The data-driven approach presented here uses large-scale plasma IgG mass spectrometry measurements to infer new biochemical reactions in the glycosylation pathway.Elisa BenedettiMaja Pučić-BakovićToma KeserAnnika WahlAntti HassinenJeong-Yeh YangLin LiuIrena Trbojević-AkmačićGenadij RazdorovJerko ŠtambukLucija KlarićIvo UgrinaMaurice H. J. SelmanManfred WuhrerIgor RudanOzren PolasekCaroline HaywardHarald GrallertKonstantin StrauchAnnette PetersThomas MeitingerChristian GiegerMarija VilajGeert-Jan BoonsKelley W. MoremenTatiana OvchinnikovaNicolai BovinSakari KellokumpuFabian J. TheisGordan LaucJan KrumsiekNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
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DOAJ |
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EN |
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Science Q |
| spellingShingle |
Science Q Elisa Benedetti Maja Pučić-Baković Toma Keser Annika Wahl Antti Hassinen Jeong-Yeh Yang Lin Liu Irena Trbojević-Akmačić Genadij Razdorov Jerko Štambuk Lucija Klarić Ivo Ugrina Maurice H. J. Selman Manfred Wuhrer Igor Rudan Ozren Polasek Caroline Hayward Harald Grallert Konstantin Strauch Annette Peters Thomas Meitinger Christian Gieger Marija Vilaj Geert-Jan Boons Kelley W. Moremen Tatiana Ovchinnikova Nicolai Bovin Sakari Kellokumpu Fabian J. Theis Gordan Lauc Jan Krumsiek Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway |
| description |
IgG glycosylation is an important factor in immune function, yet the molecular details of protein glycosylation remain poorly understood. The data-driven approach presented here uses large-scale plasma IgG mass spectrometry measurements to infer new biochemical reactions in the glycosylation pathway. |
| format |
article |
| author |
Elisa Benedetti Maja Pučić-Baković Toma Keser Annika Wahl Antti Hassinen Jeong-Yeh Yang Lin Liu Irena Trbojević-Akmačić Genadij Razdorov Jerko Štambuk Lucija Klarić Ivo Ugrina Maurice H. J. Selman Manfred Wuhrer Igor Rudan Ozren Polasek Caroline Hayward Harald Grallert Konstantin Strauch Annette Peters Thomas Meitinger Christian Gieger Marija Vilaj Geert-Jan Boons Kelley W. Moremen Tatiana Ovchinnikova Nicolai Bovin Sakari Kellokumpu Fabian J. Theis Gordan Lauc Jan Krumsiek |
| author_facet |
Elisa Benedetti Maja Pučić-Baković Toma Keser Annika Wahl Antti Hassinen Jeong-Yeh Yang Lin Liu Irena Trbojević-Akmačić Genadij Razdorov Jerko Štambuk Lucija Klarić Ivo Ugrina Maurice H. J. Selman Manfred Wuhrer Igor Rudan Ozren Polasek Caroline Hayward Harald Grallert Konstantin Strauch Annette Peters Thomas Meitinger Christian Gieger Marija Vilaj Geert-Jan Boons Kelley W. Moremen Tatiana Ovchinnikova Nicolai Bovin Sakari Kellokumpu Fabian J. Theis Gordan Lauc Jan Krumsiek |
| author_sort |
Elisa Benedetti |
| title |
Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway |
| title_short |
Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway |
| title_full |
Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway |
| title_fullStr |
Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway |
| title_full_unstemmed |
Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway |
| title_sort |
network inference from glycoproteomics data reveals new reactions in the igg glycosylation pathway |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/11aecacd968d49ca905c6b1672c3015d |
| work_keys_str_mv |
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