Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 Å resolution

Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 Å resolution

The type-I fatty acid synthase (FAS-I) complex is essential for Mycobacterium tuberculosis (Mtb) and mediates the production of C26 fatty acids that are precursors for the synthesis of mycolic acids. Here the authors present the 3.3 Å resolution cryo-EM structure of Mtb FAS-I, which is of interest f...

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Autores principales: Nadav Elad, Szilvia Baron, Yoav Peleg, Shira Albeck, Jacob Grunwald, Gal Raviv, Zippora Shakked, Oren Zimhony, Ron Diskin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/11b0d9221adb4b1bbbacb74016a4bfa6
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