Host suppression of quorum sensing during catheter-associated urinary tract infections

Pseudomonas aeruginosa can cause chronic infections on medical devices by forming biofilms, a process regulated by quorum sensing (QS). Here, the authors show that P. aeruginosa is unable to perceive QS signals in the presence of either host urine or urea, and clinical isolates are often defective i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Stephanie J. Cole, Cherisse L. Hall, Maren Schniederberend, John M. Farrow III, Jonathan R. Goodson, Everett C. Pesci, Barbara I. Kazmierczak, Vincent T. Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/11b52e4dc29b4aa1861a0d52fda5af9e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:11b52e4dc29b4aa1861a0d52fda5af9e
record_format dspace
spelling oai:doaj.org-article:11b52e4dc29b4aa1861a0d52fda5af9e2021-12-02T16:49:50ZHost suppression of quorum sensing during catheter-associated urinary tract infections10.1038/s41467-018-06882-y2041-1723https://doaj.org/article/11b52e4dc29b4aa1861a0d52fda5af9e2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06882-yhttps://doaj.org/toc/2041-1723Pseudomonas aeruginosa can cause chronic infections on medical devices by forming biofilms, a process regulated by quorum sensing (QS). Here, the authors show that P. aeruginosa is unable to perceive QS signals in the presence of either host urine or urea, and clinical isolates are often defective in QS.Stephanie J. ColeCherisse L. HallMaren SchniederberendJohn M. Farrow IIIJonathan R. GoodsonEverett C. PesciBarbara I. KazmierczakVincent T. LeeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stephanie J. Cole
Cherisse L. Hall
Maren Schniederberend
John M. Farrow III
Jonathan R. Goodson
Everett C. Pesci
Barbara I. Kazmierczak
Vincent T. Lee
Host suppression of quorum sensing during catheter-associated urinary tract infections
description Pseudomonas aeruginosa can cause chronic infections on medical devices by forming biofilms, a process regulated by quorum sensing (QS). Here, the authors show that P. aeruginosa is unable to perceive QS signals in the presence of either host urine or urea, and clinical isolates are often defective in QS.
format article
author Stephanie J. Cole
Cherisse L. Hall
Maren Schniederberend
John M. Farrow III
Jonathan R. Goodson
Everett C. Pesci
Barbara I. Kazmierczak
Vincent T. Lee
author_facet Stephanie J. Cole
Cherisse L. Hall
Maren Schniederberend
John M. Farrow III
Jonathan R. Goodson
Everett C. Pesci
Barbara I. Kazmierczak
Vincent T. Lee
author_sort Stephanie J. Cole
title Host suppression of quorum sensing during catheter-associated urinary tract infections
title_short Host suppression of quorum sensing during catheter-associated urinary tract infections
title_full Host suppression of quorum sensing during catheter-associated urinary tract infections
title_fullStr Host suppression of quorum sensing during catheter-associated urinary tract infections
title_full_unstemmed Host suppression of quorum sensing during catheter-associated urinary tract infections
title_sort host suppression of quorum sensing during catheter-associated urinary tract infections
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/11b52e4dc29b4aa1861a0d52fda5af9e
work_keys_str_mv AT stephaniejcole hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections
AT cherisselhall hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections
AT marenschniederberend hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections
AT johnmfarrowiii hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections
AT jonathanrgoodson hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections
AT everettcpesci hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections
AT barbaraikazmierczak hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections
AT vincenttlee hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections
_version_ 1718383199432736768