Host suppression of quorum sensing during catheter-associated urinary tract infections
Pseudomonas aeruginosa can cause chronic infections on medical devices by forming biofilms, a process regulated by quorum sensing (QS). Here, the authors show that P. aeruginosa is unable to perceive QS signals in the presence of either host urine or urea, and clinical isolates are often defective i...
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Nature Portfolio
2018
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oai:doaj.org-article:11b52e4dc29b4aa1861a0d52fda5af9e2021-12-02T16:49:50ZHost suppression of quorum sensing during catheter-associated urinary tract infections10.1038/s41467-018-06882-y2041-1723https://doaj.org/article/11b52e4dc29b4aa1861a0d52fda5af9e2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06882-yhttps://doaj.org/toc/2041-1723Pseudomonas aeruginosa can cause chronic infections on medical devices by forming biofilms, a process regulated by quorum sensing (QS). Here, the authors show that P. aeruginosa is unable to perceive QS signals in the presence of either host urine or urea, and clinical isolates are often defective in QS.Stephanie J. ColeCherisse L. HallMaren SchniederberendJohn M. Farrow IIIJonathan R. GoodsonEverett C. PesciBarbara I. KazmierczakVincent T. LeeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018) |
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DOAJ |
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Science Q |
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Science Q Stephanie J. Cole Cherisse L. Hall Maren Schniederberend John M. Farrow III Jonathan R. Goodson Everett C. Pesci Barbara I. Kazmierczak Vincent T. Lee Host suppression of quorum sensing during catheter-associated urinary tract infections |
description |
Pseudomonas aeruginosa can cause chronic infections on medical devices by forming biofilms, a process regulated by quorum sensing (QS). Here, the authors show that P. aeruginosa is unable to perceive QS signals in the presence of either host urine or urea, and clinical isolates are often defective in QS. |
format |
article |
author |
Stephanie J. Cole Cherisse L. Hall Maren Schniederberend John M. Farrow III Jonathan R. Goodson Everett C. Pesci Barbara I. Kazmierczak Vincent T. Lee |
author_facet |
Stephanie J. Cole Cherisse L. Hall Maren Schniederberend John M. Farrow III Jonathan R. Goodson Everett C. Pesci Barbara I. Kazmierczak Vincent T. Lee |
author_sort |
Stephanie J. Cole |
title |
Host suppression of quorum sensing during catheter-associated urinary tract infections |
title_short |
Host suppression of quorum sensing during catheter-associated urinary tract infections |
title_full |
Host suppression of quorum sensing during catheter-associated urinary tract infections |
title_fullStr |
Host suppression of quorum sensing during catheter-associated urinary tract infections |
title_full_unstemmed |
Host suppression of quorum sensing during catheter-associated urinary tract infections |
title_sort |
host suppression of quorum sensing during catheter-associated urinary tract infections |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/11b52e4dc29b4aa1861a0d52fda5af9e |
work_keys_str_mv |
AT stephaniejcole hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections AT cherisselhall hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections AT marenschniederberend hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections AT johnmfarrowiii hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections AT jonathanrgoodson hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections AT everettcpesci hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections AT barbaraikazmierczak hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections AT vincenttlee hostsuppressionofquorumsensingduringcatheterassociatedurinarytractinfections |
_version_ |
1718383199432736768 |