The Biofilm Inhibitor Carolacton Enters Gram-Negative Cells: Studies Using a TolC-Deficient Strain of <named-content content-type="genus-species">Escherichia coli</named-content>

The Biofilm Inhibitor Carolacton Enters Gram-Negative Cells: Studies Using a TolC-Deficient Strain of <named-content content-type="genus-species">Escherichia coli</named-content>

ABSTRACT The myxobacterial secondary metabolite carolacton inhibits growth of Streptococcus pneumoniae and kills biofilm cells of the caries- and endocarditis-associated pathogen Streptococcus mutans at nanomolar concentrations. Here, we studied the response to carolacton of an Escherichia coli stra...

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Bibliographic Details
Main Authors: Jannik Donner, Michael Reck, Boyke Bunk, Michael Jarek, Constantin Benjamin App, Jan P. Meier-Kolthoff, Jörg Overmann, Rolf Müller, Andreas Kirschning, Irene Wagner-Döbler
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Gram-negative bacteria
antimicrobial activity
antimicrobial agents
carolacton
drug efflux
drug resistance mechanisms
Microbiology
QR1-502
Online Access:https://doaj.org/article/11b8e6d6ef754cf5a0d7a8bd838a3564
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