Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy

The authors test expansion microscopy protocols for investigation of the molecular organisation of mammalian synaptonemal complexes (SCs) with structured illumination microscopy. They show that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed.

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Auteurs principaux: Fabian U. Zwettler, Marie-Christin Spindler, Sebastian Reinhard, Teresa Klein, Andreas Kurz, Ricardo Benavente, Markus Sauer
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/11cb7bca60d54e4b80ed2a6bc218b85c
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Résumé:The authors test expansion microscopy protocols for investigation of the molecular organisation of mammalian synaptonemal complexes (SCs) with structured illumination microscopy. They show that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed.