Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy

The authors test expansion microscopy protocols for investigation of the molecular organisation of mammalian synaptonemal complexes (SCs) with structured illumination microscopy. They show that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed.

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Autores principales: Fabian U. Zwettler, Marie-Christin Spindler, Sebastian Reinhard, Teresa Klein, Andreas Kurz, Ricardo Benavente, Markus Sauer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/11cb7bca60d54e4b80ed2a6bc218b85c
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spelling oai:doaj.org-article:11cb7bca60d54e4b80ed2a6bc218b85c2021-12-02T17:12:24ZTracking down the molecular architecture of the synaptonemal complex by expansion microscopy10.1038/s41467-020-17017-72041-1723https://doaj.org/article/11cb7bca60d54e4b80ed2a6bc218b85c2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17017-7https://doaj.org/toc/2041-1723The authors test expansion microscopy protocols for investigation of the molecular organisation of mammalian synaptonemal complexes (SCs) with structured illumination microscopy. They show that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed.Fabian U. ZwettlerMarie-Christin SpindlerSebastian ReinhardTeresa KleinAndreas KurzRicardo BenaventeMarkus SauerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Fabian U. Zwettler
Marie-Christin Spindler
Sebastian Reinhard
Teresa Klein
Andreas Kurz
Ricardo Benavente
Markus Sauer
Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
description The authors test expansion microscopy protocols for investigation of the molecular organisation of mammalian synaptonemal complexes (SCs) with structured illumination microscopy. They show that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed.
format article
author Fabian U. Zwettler
Marie-Christin Spindler
Sebastian Reinhard
Teresa Klein
Andreas Kurz
Ricardo Benavente
Markus Sauer
author_facet Fabian U. Zwettler
Marie-Christin Spindler
Sebastian Reinhard
Teresa Klein
Andreas Kurz
Ricardo Benavente
Markus Sauer
author_sort Fabian U. Zwettler
title Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_short Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_full Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_fullStr Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_full_unstemmed Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_sort tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/11cb7bca60d54e4b80ed2a6bc218b85c
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