Influence of Age, Gender and Duration of Diabetes on Serum and Urine Levels of Zinc, Magnesium, Seleniumand Chromium in Type 2 Diabetics in Calabar, Nigeria

The study aimed to demonstrate the possible effect of some variables such as age,gender and duration of diabetes on the serum and urine levels of zinc, magnesium,selenium and chromium in type 2 diabetic subjects and a control group of nondiabetic individuals. Serum and urine zinc (Zn), magnesium (Mg...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Augusta Chinyere Nsonwu, Chinyere Adanna Opara Usoro, Maisie Henrietta Etukudo, Isonguyo Nathaniel Usoro
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2006
Materias:
Age
Acceso en línea:https://doaj.org/article/11cbfa72c35f40fba27fb4a4cce143ba
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:11cbfa72c35f40fba27fb4a4cce143ba
record_format dspace
spelling oai:doaj.org-article:11cbfa72c35f40fba27fb4a4cce143ba2021-12-02T11:55:49ZInfluence of Age, Gender and Duration of Diabetes on Serum and Urine Levels of Zinc, Magnesium, Seleniumand Chromium in Type 2 Diabetics in Calabar, Nigeria 0250-46851303-829Xhttps://doaj.org/article/11cbfa72c35f40fba27fb4a4cce143ba2006-09-01T00:00:00Zhttp://www.turkjbiochem.com/2006/107_114.pdfhttps://doaj.org/toc/0250-4685https://doaj.org/toc/1303-829XThe study aimed to demonstrate the possible effect of some variables such as age,gender and duration of diabetes on the serum and urine levels of zinc, magnesium,selenium and chromium in type 2 diabetic subjects and a control group of nondiabetic individuals. Serum and urine zinc (Zn), magnesium (Mg), selenium (Se), chromium (Cr) and creatinine; fasting plasma glucose (FPG) and serum urea levelswere determined in 60 diabetic subjects of both genders aged between 40-75 years and 40 age matched non diabetic subjects from Calabar, Nigeria using colorimetric methods and atomic absorption spectrophotometry (AAS). Elderly diabetics (55-75) have significantly (p<0.05) lower serum Se and Cr and higher urinary traceelements than the younger age group (40-54). Female diabetics have significantly (p<0.05) higher serum Zn and Se and lower urinary Mg and Zn than diabetic males. Serum and urine trace elements concentrations varied significantly (p<0.05) with the duration of diabetes. Aging and increasing duration of diabetes alters the metabolism of Zinc, Magnesium, Selenium and Chromium by decreasing their serum concentration and increasing their urinary excretion. The gender related differences in trace element levels in diabetics, might be attributed to hormonal imbalance associated with the diabetic state.Augusta Chinyere NsonwuChinyere Adanna Opara UsoroMaisie Henrietta EtukudoIsonguyo Nathaniel UsoroDe GruyterarticleType 2 diabeticsAgeGenderZincMagnesiumSeleniumChromiumBiochemistryQD415-436ENTürk Biyokimya Dergisi, Pp 107-114 (2006)
institution DOAJ
collection DOAJ
language EN
topic Type 2 diabetics
Age
Gender
Zinc
Magnesium
Selenium
Chromium
Biochemistry
QD415-436
spellingShingle Type 2 diabetics
Age
Gender
Zinc
Magnesium
Selenium
Chromium
Biochemistry
QD415-436
Augusta Chinyere Nsonwu
Chinyere Adanna Opara Usoro
Maisie Henrietta Etukudo
Isonguyo Nathaniel Usoro
Influence of Age, Gender and Duration of Diabetes on Serum and Urine Levels of Zinc, Magnesium, Seleniumand Chromium in Type 2 Diabetics in Calabar, Nigeria
description The study aimed to demonstrate the possible effect of some variables such as age,gender and duration of diabetes on the serum and urine levels of zinc, magnesium,selenium and chromium in type 2 diabetic subjects and a control group of nondiabetic individuals. Serum and urine zinc (Zn), magnesium (Mg), selenium (Se), chromium (Cr) and creatinine; fasting plasma glucose (FPG) and serum urea levelswere determined in 60 diabetic subjects of both genders aged between 40-75 years and 40 age matched non diabetic subjects from Calabar, Nigeria using colorimetric methods and atomic absorption spectrophotometry (AAS). Elderly diabetics (55-75) have significantly (p<0.05) lower serum Se and Cr and higher urinary traceelements than the younger age group (40-54). Female diabetics have significantly (p<0.05) higher serum Zn and Se and lower urinary Mg and Zn than diabetic males. Serum and urine trace elements concentrations varied significantly (p<0.05) with the duration of diabetes. Aging and increasing duration of diabetes alters the metabolism of Zinc, Magnesium, Selenium and Chromium by decreasing their serum concentration and increasing their urinary excretion. The gender related differences in trace element levels in diabetics, might be attributed to hormonal imbalance associated with the diabetic state.
format article
author Augusta Chinyere Nsonwu
Chinyere Adanna Opara Usoro
Maisie Henrietta Etukudo
Isonguyo Nathaniel Usoro
author_facet Augusta Chinyere Nsonwu
Chinyere Adanna Opara Usoro
Maisie Henrietta Etukudo
Isonguyo Nathaniel Usoro
author_sort Augusta Chinyere Nsonwu
title Influence of Age, Gender and Duration of Diabetes on Serum and Urine Levels of Zinc, Magnesium, Seleniumand Chromium in Type 2 Diabetics in Calabar, Nigeria
title_short Influence of Age, Gender and Duration of Diabetes on Serum and Urine Levels of Zinc, Magnesium, Seleniumand Chromium in Type 2 Diabetics in Calabar, Nigeria
title_full Influence of Age, Gender and Duration of Diabetes on Serum and Urine Levels of Zinc, Magnesium, Seleniumand Chromium in Type 2 Diabetics in Calabar, Nigeria
title_fullStr Influence of Age, Gender and Duration of Diabetes on Serum and Urine Levels of Zinc, Magnesium, Seleniumand Chromium in Type 2 Diabetics in Calabar, Nigeria
title_full_unstemmed Influence of Age, Gender and Duration of Diabetes on Serum and Urine Levels of Zinc, Magnesium, Seleniumand Chromium in Type 2 Diabetics in Calabar, Nigeria
title_sort influence of age, gender and duration of diabetes on serum and urine levels of zinc, magnesium, seleniumand chromium in type 2 diabetics in calabar, nigeria
publisher De Gruyter
publishDate 2006
url https://doaj.org/article/11cbfa72c35f40fba27fb4a4cce143ba
work_keys_str_mv AT augustachinyerensonwu influenceofagegenderanddurationofdiabetesonserumandurinelevelsofzincmagnesiumseleniumandchromiumintype2diabeticsincalabarnigeria
AT chinyereadannaoparausoro influenceofagegenderanddurationofdiabetesonserumandurinelevelsofzincmagnesiumseleniumandchromiumintype2diabeticsincalabarnigeria
AT maisiehenriettaetukudo influenceofagegenderanddurationofdiabetesonserumandurinelevelsofzincmagnesiumseleniumandchromiumintype2diabeticsincalabarnigeria
AT isonguyonathanielusoro influenceofagegenderanddurationofdiabetesonserumandurinelevelsofzincmagnesiumseleniumandchromiumintype2diabeticsincalabarnigeria
_version_ 1718394790876282880