Comparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical Markers

Background Data: Discectomy through a limited laminotomy has remained the “gold standard” for lumbar disc surgery. Surgery for lumbar disc herniation can be classified into two broad categories;open (conventional) versus minimally invasive surgery, where the last category classified into microscopic...

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Autores principales:	Mohamed Abbas, Amr Elwany, Refaat Mohamed
Formato:	article
Lenguaje:	EN
Publicado:	Egyptian Spine Association 2018
Materias:	microscopic discectomy microendoscopic discectomy CRP CPK Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/11d51b31d3074f21a5b7ca4b70cc5e93
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spelling	oai:doaj.org-article:11d51b31d3074f21a5b7ca4b70cc5e932021-12-02T03:08:52ZComparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical MarkersDOI:10.21608/ESJ.2018.112402314-89502314-8969https://doaj.org/article/11d51b31d3074f21a5b7ca4b70cc5e932018-04-01T00:00:00Zhttp://www.esj.journals.ekb.eg/article_11240.htmlhttps://doaj.org/toc/2314-8950https://doaj.org/toc/2314-8969Background Data: Discectomy through a limited laminotomy has remained the “gold standard” for lumbar disc surgery. Surgery for lumbar disc herniation can be classified into two broad categories;open (conventional) versus minimally invasive surgery, where the last category classified into microscopic, endoscopic and percutaneous procedures. Microendoscopic discectomy (MED) is unique in that it combines open surgical principles with endoscopic technology. Purpose: To evaluate extent of tissue damage and pain relief after microendoscopic (MED) and microscopic lumbar discectomy (MD). Study Design: A prospective randomized controlled study. Patients and Methods: The study included 40 patients having lumbar disc prolapse, operated in Alexandria Main University Hospital. Twenty of them underwent MED (Group A) and the other twenty underwent MD (Group B). Clinical (VAS, ODI) and radiological and biochemical markers (CRP, CPK) for tissue inflammation data were collected preoperatively and postoperatively for comparison. Patients were followed up for 6 months. Results: 26 patients were males and 14 were females. The mean age for group A was 40.8±1.34 years and for group B was 40.2±1.06 years. Clinically all patients had low back pain and radicular leg pain. There was no statistically significant difference between the duration of surgery in both groups. The length of hospital stay was significantly less in MED group. The length of the skin wound was significantly less in MED group. Reduction of back pain VAS immediate and 1 month postoperative was reported in both groups and was statistically significantly better in MED group, however, after 6 months there was no difference between both groups. There was significant improvement with no difference between both groups regarding radicular VAS and ODI all through the follow up. Postoperative CRP and CPK was statistically significantly higher in MD group (P<0.001). Conclusion: Both techniques gave comparable clinical outcomes although early back pain score and tissue markers were in favor of MED technique. (2018ESJ153)Mohamed AbbasAmr ElwanyRefaat MohamedEgyptian Spine Associationarticlemicroscopic discectomymicroendoscopic discectomyCRPCPKNeurology. Diseases of the nervous systemRC346-429ENEgyptian Spine Journal, Vol 26, Iss 1, Pp 25-33 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	microscopic discectomy microendoscopic discectomy CRP CPK Neurology. Diseases of the nervous system RC346-429
spellingShingle	microscopic discectomy microendoscopic discectomy CRP CPK Neurology. Diseases of the nervous system RC346-429 Mohamed Abbas Amr Elwany Refaat Mohamed Comparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical Markers
description	Background Data: Discectomy through a limited laminotomy has remained the “gold standard” for lumbar disc surgery. Surgery for lumbar disc herniation can be classified into two broad categories;open (conventional) versus minimally invasive surgery, where the last category classified into microscopic, endoscopic and percutaneous procedures. Microendoscopic discectomy (MED) is unique in that it combines open surgical principles with endoscopic technology. Purpose: To evaluate extent of tissue damage and pain relief after microendoscopic (MED) and microscopic lumbar discectomy (MD). Study Design: A prospective randomized controlled study. Patients and Methods: The study included 40 patients having lumbar disc prolapse, operated in Alexandria Main University Hospital. Twenty of them underwent MED (Group A) and the other twenty underwent MD (Group B). Clinical (VAS, ODI) and radiological and biochemical markers (CRP, CPK) for tissue inflammation data were collected preoperatively and postoperatively for comparison. Patients were followed up for 6 months. Results: 26 patients were males and 14 were females. The mean age for group A was 40.8±1.34 years and for group B was 40.2±1.06 years. Clinically all patients had low back pain and radicular leg pain. There was no statistically significant difference between the duration of surgery in both groups. The length of hospital stay was significantly less in MED group. The length of the skin wound was significantly less in MED group. Reduction of back pain VAS immediate and 1 month postoperative was reported in both groups and was statistically significantly better in MED group, however, after 6 months there was no difference between both groups. There was significant improvement with no difference between both groups regarding radicular VAS and ODI all through the follow up. Postoperative CRP and CPK was statistically significantly higher in MD group (P<0.001). Conclusion: Both techniques gave comparable clinical outcomes although early back pain score and tissue markers were in favor of MED technique. (2018ESJ153)
format	article
author	Mohamed Abbas Amr Elwany Refaat Mohamed
author_facet	Mohamed Abbas Amr Elwany Refaat Mohamed
author_sort	Mohamed Abbas
title	Comparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical Markers
title_short	Comparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical Markers
title_full	Comparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical Markers
title_fullStr	Comparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical Markers
title_full_unstemmed	Comparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical Markers
title_sort	comparing the extent of tissue damage between lumbar microendoscopic discectomy (med) and microscopic discectomy (md) using biochemical markers
publisher	Egyptian Spine Association
publishDate	2018
url	https://doaj.org/article/11d51b31d3074f21a5b7ca4b70cc5e93
work_keys_str_mv	AT mohamedabbas comparingtheextentoftissuedamagebetweenlumbarmicroendoscopicdiscectomymedandmicroscopicdiscectomymdusingbiochemicalmarkers AT amrelwany comparingtheextentoftissuedamagebetweenlumbarmicroendoscopicdiscectomymedandmicroscopicdiscectomymdusingbiochemicalmarkers AT refaatmohamed comparingtheextentoftissuedamagebetweenlumbarmicroendoscopicdiscectomymedandmicroscopicdiscectomymdusingbiochemicalmarkers
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Comparing the Extent of Tissue Damage between Lumbar Microendoscopic Discectomy (MED) and Microscopic Discectomy (MD) Using Biochemical Markers

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