A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice

Understanding how cells maintain tissues is challenging. Here, the authors present a single consistent quantitative approach to analyse cell proliferation and lineage tracing data, which shows a single proliferating cell population that maintains epidermal and esophageal epithelial homeostasis.

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Autores principales: Gabriel Piedrafita, Vasiliki Kostiou, Agnieszka Wabik, Bartomeu Colom, David Fernandez-Antoran, Albert Herms, Kasumi Murai, Benjamin A. Hall, Philip H. Jones
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/11e1473f6ed64141ac21fbcd3f57b93b
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spelling oai:doaj.org-article:11e1473f6ed64141ac21fbcd3f57b93b2021-12-02T17:31:11ZA single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice10.1038/s41467-020-15258-02041-1723https://doaj.org/article/11e1473f6ed64141ac21fbcd3f57b93b2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15258-0https://doaj.org/toc/2041-1723Understanding how cells maintain tissues is challenging. Here, the authors present a single consistent quantitative approach to analyse cell proliferation and lineage tracing data, which shows a single proliferating cell population that maintains epidermal and esophageal epithelial homeostasis.Gabriel PiedrafitaVasiliki KostiouAgnieszka WabikBartomeu ColomDavid Fernandez-AntoranAlbert HermsKasumi MuraiBenjamin A. HallPhilip H. JonesNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gabriel Piedrafita
Vasiliki Kostiou
Agnieszka Wabik
Bartomeu Colom
David Fernandez-Antoran
Albert Herms
Kasumi Murai
Benjamin A. Hall
Philip H. Jones
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
description Understanding how cells maintain tissues is challenging. Here, the authors present a single consistent quantitative approach to analyse cell proliferation and lineage tracing data, which shows a single proliferating cell population that maintains epidermal and esophageal epithelial homeostasis.
format article
author Gabriel Piedrafita
Vasiliki Kostiou
Agnieszka Wabik
Bartomeu Colom
David Fernandez-Antoran
Albert Herms
Kasumi Murai
Benjamin A. Hall
Philip H. Jones
author_facet Gabriel Piedrafita
Vasiliki Kostiou
Agnieszka Wabik
Bartomeu Colom
David Fernandez-Antoran
Albert Herms
Kasumi Murai
Benjamin A. Hall
Philip H. Jones
author_sort Gabriel Piedrafita
title A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
title_short A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
title_full A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
title_fullStr A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
title_full_unstemmed A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
title_sort single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/11e1473f6ed64141ac21fbcd3f57b93b
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