A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
Understanding how cells maintain tissues is challenging. Here, the authors present a single consistent quantitative approach to analyse cell proliferation and lineage tracing data, which shows a single proliferating cell population that maintains epidermal and esophageal epithelial homeostasis.
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Nature Portfolio
2020
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oai:doaj.org-article:11e1473f6ed64141ac21fbcd3f57b93b2021-12-02T17:31:11ZA single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice10.1038/s41467-020-15258-02041-1723https://doaj.org/article/11e1473f6ed64141ac21fbcd3f57b93b2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15258-0https://doaj.org/toc/2041-1723Understanding how cells maintain tissues is challenging. Here, the authors present a single consistent quantitative approach to analyse cell proliferation and lineage tracing data, which shows a single proliferating cell population that maintains epidermal and esophageal epithelial homeostasis.Gabriel PiedrafitaVasiliki KostiouAgnieszka WabikBartomeu ColomDavid Fernandez-AntoranAlbert HermsKasumi MuraiBenjamin A. HallPhilip H. JonesNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Gabriel Piedrafita Vasiliki Kostiou Agnieszka Wabik Bartomeu Colom David Fernandez-Antoran Albert Herms Kasumi Murai Benjamin A. Hall Philip H. Jones A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice |
description |
Understanding how cells maintain tissues is challenging. Here, the authors present a single consistent quantitative approach to analyse cell proliferation and lineage tracing data, which shows a single proliferating cell population that maintains epidermal and esophageal epithelial homeostasis. |
format |
article |
author |
Gabriel Piedrafita Vasiliki Kostiou Agnieszka Wabik Bartomeu Colom David Fernandez-Antoran Albert Herms Kasumi Murai Benjamin A. Hall Philip H. Jones |
author_facet |
Gabriel Piedrafita Vasiliki Kostiou Agnieszka Wabik Bartomeu Colom David Fernandez-Antoran Albert Herms Kasumi Murai Benjamin A. Hall Philip H. Jones |
author_sort |
Gabriel Piedrafita |
title |
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice |
title_short |
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice |
title_full |
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice |
title_fullStr |
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice |
title_full_unstemmed |
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice |
title_sort |
single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/11e1473f6ed64141ac21fbcd3f57b93b |
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