Tunable multiphase dynamics of arginine and lysine liquid condensates

The design principles underlying biomolecular phase separation of membrane-less organelles remain poorly understood. Using model homopolymers, Fisher et al. show that the formation kinetics of coexisting liquid phases can be tuned by exploiting differences between arginine and lysine residues.

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Detalles Bibliográficos
Autores principales:	Rachel S. Fisher, Shana Elbaum-Garfinkle
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/11f495e04dff484c867794c842249df7
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spelling	oai:doaj.org-article:11f495e04dff484c867794c842249df72021-12-02T17:24:13ZTunable multiphase dynamics of arginine and lysine liquid condensates10.1038/s41467-020-18224-y2041-1723https://doaj.org/article/11f495e04dff484c867794c842249df72020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18224-yhttps://doaj.org/toc/2041-1723The design principles underlying biomolecular phase separation of membrane-less organelles remain poorly understood. Using model homopolymers, Fisher et al. show that the formation kinetics of coexisting liquid phases can be tuned by exploiting differences between arginine and lysine residues.Rachel S. FisherShana Elbaum-GarfinkleNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rachel S. Fisher Shana Elbaum-Garfinkle Tunable multiphase dynamics of arginine and lysine liquid condensates
description	The design principles underlying biomolecular phase separation of membrane-less organelles remain poorly understood. Using model homopolymers, Fisher et al. show that the formation kinetics of coexisting liquid phases can be tuned by exploiting differences between arginine and lysine residues.
format	article
author	Rachel S. Fisher Shana Elbaum-Garfinkle
author_facet	Rachel S. Fisher Shana Elbaum-Garfinkle
author_sort	Rachel S. Fisher
title	Tunable multiphase dynamics of arginine and lysine liquid condensates
title_short	Tunable multiphase dynamics of arginine and lysine liquid condensates
title_full	Tunable multiphase dynamics of arginine and lysine liquid condensates
title_fullStr	Tunable multiphase dynamics of arginine and lysine liquid condensates
title_full_unstemmed	Tunable multiphase dynamics of arginine and lysine liquid condensates
title_sort	tunable multiphase dynamics of arginine and lysine liquid condensates
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/11f495e04dff484c867794c842249df7
work_keys_str_mv	AT rachelsfisher tunablemultiphasedynamicsofarginineandlysineliquidcondensates AT shanaelbaumgarfinkle tunablemultiphasedynamicsofarginineandlysineliquidcondensates
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Tunable multiphase dynamics of arginine and lysine liquid condensates

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