Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum

Abstract. Prastiyanto ME, Rohmah N, Efendi L, Arifin R, Wardoyo FA, Wilson W, Mukaromah AH, Dewi SS, Darmawati S. 2021. Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum. Biodiversitas 22: 1509-1513. Fungal infections have now...

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Autores principales: Muhammad Evy Prastiyanto, NI’MATUR ROHMAH, LESITA EFENDI, RAHMATIA ARIFIN, FANDHI ADI WARDOYO, WILDIANI WILSON, ANA HIDAYATI MUKAROMAH, SRI SINTO DEWI, SRI DARMAWATI
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Publicado: MBI & UNS Solo 2021
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spelling oai:doaj.org-article:120c09af47bc47be947521c26ae77f2a2021-11-22T00:56:36ZAntifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum1412-033X2085-472210.13057/biodiv/d220355https://doaj.org/article/120c09af47bc47be947521c26ae77f2a2021-03-01T00:00:00Zhttps://smujo.id/biodiv/article/view/7217https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Prastiyanto ME, Rohmah N, Efendi L, Arifin R, Wardoyo FA, Wilson W, Mukaromah AH, Dewi SS, Darmawati S. 2021. Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum. Biodiversitas 22: 1509-1513. Fungal infections have now become serious health issues. One of the strategies to avoid the problems of fungal infections is by using natural product from plants that are effective against many human pathogenic fungi. The study portrayed the use of the extracts of plant rhizomes as the alternatives to fight against number of human pathogenic fungi. This research aimed to investigate the antifungal activities of crude ethanol extract of five member of the family Zingiberaceae (Curcuma longa, Alpinia galanga Zingiber officinale. var. rubrum, Zingiber officinale var. officinarum and Zingiber officinale var. amarum), which are widely used as folk medicines against Candida albicans and Trichophyton rubrum. Crude ethanol extracts of five members of Zingiberaceae were evaluated for their antifungal activities and the results were calculated based on the zones of inhibition using the diffusion method. The extract showed antifungal activity against Candida. albicans in the agar well diffusion assay (10.2-27.1 mm inhibition diameter) and against T. rubrum (27.3-44.3 mm inhibition diameter). The data have revealed that all rhizomes have the potential to be developed as antifungal agents, particularly against C. albicans and T. rubrum. Studies on the antifungal activity against yeast-like (C. albicans) and filamentous (T. rubrum) can provide new information about the benefits of members Zingiberaceae as a source of natural antifungal. Researchers can select the type of rhizome that has more potential for further extraction to obtain pure compounds that can be used as antifungals.Muhammad Evy PrastiyantoNI’MATUR ROHMAHLESITA EFENDIRAHMATIA ARIFINFANDHI ADI WARDOYOWILDIANI WILSONANA HIDAYATI MUKAROMAHSRI SINTO DEWISRI DARMAWATIMBI & UNS Soloarticleantifungal activity, candida albicans, trichophyton rubrum, zingiberaceae, zones of inhibitionBiology (General)QH301-705.5ENBiodiversitas, Vol 22, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic antifungal activity, candida albicans, trichophyton rubrum, zingiberaceae, zones of inhibition
Biology (General)
QH301-705.5
spellingShingle antifungal activity, candida albicans, trichophyton rubrum, zingiberaceae, zones of inhibition
Biology (General)
QH301-705.5
Muhammad Evy Prastiyanto
NI’MATUR ROHMAH
LESITA EFENDI
RAHMATIA ARIFIN
FANDHI ADI WARDOYO
WILDIANI WILSON
ANA HIDAYATI MUKAROMAH
SRI SINTO DEWI
SRI DARMAWATI
Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum
description Abstract. Prastiyanto ME, Rohmah N, Efendi L, Arifin R, Wardoyo FA, Wilson W, Mukaromah AH, Dewi SS, Darmawati S. 2021. Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum. Biodiversitas 22: 1509-1513. Fungal infections have now become serious health issues. One of the strategies to avoid the problems of fungal infections is by using natural product from plants that are effective against many human pathogenic fungi. The study portrayed the use of the extracts of plant rhizomes as the alternatives to fight against number of human pathogenic fungi. This research aimed to investigate the antifungal activities of crude ethanol extract of five member of the family Zingiberaceae (Curcuma longa, Alpinia galanga Zingiber officinale. var. rubrum, Zingiber officinale var. officinarum and Zingiber officinale var. amarum), which are widely used as folk medicines against Candida albicans and Trichophyton rubrum. Crude ethanol extracts of five members of Zingiberaceae were evaluated for their antifungal activities and the results were calculated based on the zones of inhibition using the diffusion method. The extract showed antifungal activity against Candida. albicans in the agar well diffusion assay (10.2-27.1 mm inhibition diameter) and against T. rubrum (27.3-44.3 mm inhibition diameter). The data have revealed that all rhizomes have the potential to be developed as antifungal agents, particularly against C. albicans and T. rubrum. Studies on the antifungal activity against yeast-like (C. albicans) and filamentous (T. rubrum) can provide new information about the benefits of members Zingiberaceae as a source of natural antifungal. Researchers can select the type of rhizome that has more potential for further extraction to obtain pure compounds that can be used as antifungals.
format article
author Muhammad Evy Prastiyanto
NI’MATUR ROHMAH
LESITA EFENDI
RAHMATIA ARIFIN
FANDHI ADI WARDOYO
WILDIANI WILSON
ANA HIDAYATI MUKAROMAH
SRI SINTO DEWI
SRI DARMAWATI
author_facet Muhammad Evy Prastiyanto
NI’MATUR ROHMAH
LESITA EFENDI
RAHMATIA ARIFIN
FANDHI ADI WARDOYO
WILDIANI WILSON
ANA HIDAYATI MUKAROMAH
SRI SINTO DEWI
SRI DARMAWATI
author_sort Muhammad Evy Prastiyanto
title Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum
title_short Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum
title_full Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum
title_fullStr Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum
title_full_unstemmed Antifungal activities of the rhizome extract of five member Zingiberaceae against Candida albicans and Trichophyton rubrum
title_sort antifungal activities of the rhizome extract of five member zingiberaceae against candida albicans and trichophyton rubrum
publisher MBI & UNS Solo
publishDate 2021
url https://doaj.org/article/120c09af47bc47be947521c26ae77f2a
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