Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology

Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology

Compared to bulk data, cell-type-specific DNA methylation data provide higher resolution of epigenetic variation. Here, the authors introduce Tensor Composition Analysis, a novel computational approach for learning cell-type-specific DNA methylation from tissue-level bulk data, and show its applicat...

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Autores principales: Elior Rahmani, Regev Schweiger, Brooke Rhead, Lindsey A. Criswell, Lisa F. Barcellos, Eleazar Eskin, Saharon Rosset, Sriram Sankararaman, Eran Halperin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/120d561a07024d518d2de3464a531e81
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