Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology
Compared to bulk data, cell-type-specific DNA methylation data provide higher resolution of epigenetic variation. Here, the authors introduce Tensor Composition Analysis, a novel computational approach for learning cell-type-specific DNA methylation from tissue-level bulk data, and show its applicat...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/120d561a07024d518d2de3464a531e81 |
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