Insights from zebrafish and mouse models on the activity and safety of ar-turmerone as a potential drug candidate for the treatment of epilepsy.
In a previous study, we uncovered the anticonvulsant properties of turmeric oil and its sesquiterpenoids (ar-turmerone, α-, β-turmerone and α-atlantone) in both zebrafish and mouse models of chemically-induced seizures using pentylenetetrazole (PTZ). In this follow-up study, we aimed at evaluating t...
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Autores principales: | Adriana Monserrath Orellana-Paucar, Tatiana Afrikanova, Joice Thomas, Yelaman K Aibuldinov, Wim Dehaen, Peter A M de Witte, Camila V Esguerra |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/1213b325c15d4be3bc4e47acd0b436e8 |
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