TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription

The general transcription factors TFIIE and TFIIH assemble at the transcription start site with RNA Polymerase II. Here the authors provide evidence that the TFIIEα and TFIIEβ subunits anchor the TFIIH kinase module within the preinitiation complex before their release during transcription.

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Autores principales: Emmanuel Compe, Carlos M. Genes, Cathy Braun, Frederic Coin, Jean-Marc Egly
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/121d77056e3d4d43a399accbfabcc5df
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spelling oai:doaj.org-article:121d77056e3d4d43a399accbfabcc5df2021-12-02T14:35:43ZTFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription10.1038/s41467-019-10131-12041-1723https://doaj.org/article/121d77056e3d4d43a399accbfabcc5df2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10131-1https://doaj.org/toc/2041-1723The general transcription factors TFIIE and TFIIH assemble at the transcription start site with RNA Polymerase II. Here the authors provide evidence that the TFIIEα and TFIIEβ subunits anchor the TFIIH kinase module within the preinitiation complex before their release during transcription.Emmanuel CompeCarlos M. GenesCathy BraunFrederic CoinJean-Marc EglyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Emmanuel Compe
Carlos M. Genes
Cathy Braun
Frederic Coin
Jean-Marc Egly
TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription
description The general transcription factors TFIIE and TFIIH assemble at the transcription start site with RNA Polymerase II. Here the authors provide evidence that the TFIIEα and TFIIEβ subunits anchor the TFIIH kinase module within the preinitiation complex before their release during transcription.
format article
author Emmanuel Compe
Carlos M. Genes
Cathy Braun
Frederic Coin
Jean-Marc Egly
author_facet Emmanuel Compe
Carlos M. Genes
Cathy Braun
Frederic Coin
Jean-Marc Egly
author_sort Emmanuel Compe
title TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription
title_short TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription
title_full TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription
title_fullStr TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription
title_full_unstemmed TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription
title_sort tfiie orchestrates the recruitment of the tfiih kinase module at promoter before release during transcription
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/121d77056e3d4d43a399accbfabcc5df
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