The cellular prion protein negatively regulates phagocytosis and cytokine expression in murine bone marrow-derived macrophages.
The cellular prion protein (PrP(C)) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein on the cell surface. Previous studies have demonstrated contradictory roles for PrP(C) in connection with the phagocytic ability of macrophages. In the present work, we investigated the function of PrP(...
Guardado en:
Autores principales: | Min Wang, Deming Zhao, Yang Yang, Jin Liu, Jin Wang, Xiaomin Yin, Lifeng Yang, Xiangmei Zhou |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/122eb12b06284bcf86f6088a642690f6 |
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