Single-molecule sequencing detection of N6-methyladenine in microbial reference materials
N6-methyladenine is involved in many biological pathways for microbial survival and host interaction. Here the authors train a neural network for improved m6A detection in nanopore sequencing data and validate methylomes for a microbial reference community.
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Autores principales: | Alexa B. R. McIntyre, Noah Alexander, Kirill Grigorev, Daniela Bezdan, Heike Sichtig, Charles Y. Chiu, Christopher E. Mason |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/1230778b6f7c4c39bf87c3285ae9672e |
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