Single-molecule sequencing detection of N6-methyladenine in microbial reference materials

N6-methyladenine is involved in many biological pathways for microbial survival and host interaction. Here the authors train a neural network for improved m6A detection in nanopore sequencing data and validate methylomes for a microbial reference community.

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Autores principales: Alexa B. R. McIntyre, Noah Alexander, Kirill Grigorev, Daniela Bezdan, Heike Sichtig, Charles Y. Chiu, Christopher E. Mason
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1230778b6f7c4c39bf87c3285ae9672e
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