Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician

Kate E Findeisen,1,* Julia Sewell,1,* Andrew JK Ostor2,3 1The Alfred Hospital, Melbourne, Victoria, Australia; 2Cabrini Medical Centre, Melbourne, Victoria, Australia; 3Monash University, Melbourne, Victoria, Australia*These authors contributed equally to this workCorresponde...

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Autores principales: Findeisen KE, Sewell J, Ostor AJK
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Lenguaje:EN
Publicado: Dove Medical Press 2021
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Acceso en línea:https://doaj.org/article/1232703be5704c69bbb462766b8c6605
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spelling oai:doaj.org-article:1232703be5704c69bbb462766b8c66052021-12-02T18:50:07ZBiological Therapies for Rheumatoid Arthritis: An Overview for the Clinician1177-5491https://doaj.org/article/1232703be5704c69bbb462766b8c66052021-08-01T00:00:00Zhttps://www.dovepress.com/biological-therapies-for-rheumatoid-arthritis-an-overview-for-the-clin-peer-reviewed-fulltext-article-BTThttps://doaj.org/toc/1177-5491Kate E Findeisen,1,* Julia Sewell,1,* Andrew JK Ostor2,3 1The Alfred Hospital, Melbourne, Victoria, Australia; 2Cabrini Medical Centre, Melbourne, Victoria, Australia; 3Monash University, Melbourne, Victoria, Australia*These authors contributed equally to this workCorrespondence: Andrew JK OstorCabrini Medical Centre, Melbourne, Victoria, AustraliaTel +61 3 9509 4244Email andrewostor@gmail.comAbstract: Rheumatoid arthritis (RA) is a disease characterised by inflammation of synovial joints and poses a substantial healthcare burden on both the individual and society. One of the most significant shifts in the RA therapeutic landscape has occurred with the introduction of biological disease modifying anti-rheumatic drugs (bDMARDs). There are five classes of bDMARDs currently available, each with a different molecular target and subtle differences in their efficacy and safety profile. This review also describes the “real-world” use of bDMARDs and how they fit into the overall RA treatment guidelines.Keywords: rheumatoid arthritis, biological therapies, bDMARDsFindeisen KESewell JOstor AJKDove Medical Pressarticlerheumatoid arthritisbiological therapiesbdmardsMedicine (General)R5-920ENBiologics: Targets & Therapy, Vol Volume 15, Pp 343-352 (2021)
institution DOAJ
collection DOAJ
language EN
topic rheumatoid arthritis
biological therapies
bdmards
Medicine (General)
R5-920
spellingShingle rheumatoid arthritis
biological therapies
bdmards
Medicine (General)
R5-920
Findeisen KE
Sewell J
Ostor AJK
Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician
description Kate E Findeisen,1,* Julia Sewell,1,* Andrew JK Ostor2,3 1The Alfred Hospital, Melbourne, Victoria, Australia; 2Cabrini Medical Centre, Melbourne, Victoria, Australia; 3Monash University, Melbourne, Victoria, Australia*These authors contributed equally to this workCorrespondence: Andrew JK OstorCabrini Medical Centre, Melbourne, Victoria, AustraliaTel +61 3 9509 4244Email andrewostor@gmail.comAbstract: Rheumatoid arthritis (RA) is a disease characterised by inflammation of synovial joints and poses a substantial healthcare burden on both the individual and society. One of the most significant shifts in the RA therapeutic landscape has occurred with the introduction of biological disease modifying anti-rheumatic drugs (bDMARDs). There are five classes of bDMARDs currently available, each with a different molecular target and subtle differences in their efficacy and safety profile. This review also describes the “real-world” use of bDMARDs and how they fit into the overall RA treatment guidelines.Keywords: rheumatoid arthritis, biological therapies, bDMARDs
format article
author Findeisen KE
Sewell J
Ostor AJK
author_facet Findeisen KE
Sewell J
Ostor AJK
author_sort Findeisen KE
title Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician
title_short Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician
title_full Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician
title_fullStr Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician
title_full_unstemmed Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician
title_sort biological therapies for rheumatoid arthritis: an overview for the clinician
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/1232703be5704c69bbb462766b8c6605
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