Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults

Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults

Occurrence of lower respiratory tract infections requires prior colonization of the upper respiratory tract with a pathogen. Most bacterial infection and colonization studies have been performed in murine and in vitro

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Autores principales: Elissavet Nikolaou, Simon P. Jochems, Elena Mitsi, Sherin Pojar, Annie Blizard, Jesus Reiné, Carla Solórzano, Edessa Negera, Beatriz Carniel, Alessandra Soares-Schanoski, Victoria Connor, Hugh Adler, Seher R. Zaidi, Caz Hales, Helen Hill, Angie Hyder-Wright, Stephen B. Gordon, Jamie Rylance, Daniela M. Ferreira
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/1236366ad73a46a3aea687a3e4c72662
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spelling oai:doaj.org-article:1236366ad73a46a3aea687a3e4c726622021-11-03T18:15:37ZExperimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults2161-21292150-751110.1128/mBio.02020-20https://doaj.org/article/1236366ad73a46a3aea687a3e4c726622021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02020-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Occurrence of lower respiratory tract infections requires prior colonization of the upper respiratory tract with a pathogen. Most bacterial infection and colonization studies have been performed in murine and in vitroElissavet NikolaouSimon P. JochemsElena MitsiSherin PojarAnnie BlizardJesus ReinéCarla SolórzanoEdessa NegeraBeatriz CarnielAlessandra Soares-SchanoskiVictoria ConnorHugh AdlerSeher R. ZaidiCaz HalesHelen HillAngie Hyder-WrightStephen B. GordonJamie RylanceDaniela M. FerreiraAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Elissavet Nikolaou
Simon P. Jochems
Elena Mitsi
Sherin Pojar
Annie Blizard
Jesus Reiné
Carla Solórzano
Edessa Negera
Beatriz Carniel
Alessandra Soares-Schanoski
Victoria Connor
Hugh Adler
Seher R. Zaidi
Caz Hales
Helen Hill
Angie Hyder-Wright
Stephen B. Gordon
Jamie Rylance
Daniela M. Ferreira
Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults
description Occurrence of lower respiratory tract infections requires prior colonization of the upper respiratory tract with a pathogen. Most bacterial infection and colonization studies have been performed in murine and in vitro
format article
author Elissavet Nikolaou
Simon P. Jochems
Elena Mitsi
Sherin Pojar
Annie Blizard
Jesus Reiné
Carla Solórzano
Edessa Negera
Beatriz Carniel
Alessandra Soares-Schanoski
Victoria Connor
Hugh Adler
Seher R. Zaidi
Caz Hales
Helen Hill
Angie Hyder-Wright
Stephen B. Gordon
Jamie Rylance
Daniela M. Ferreira
author_facet Elissavet Nikolaou
Simon P. Jochems
Elena Mitsi
Sherin Pojar
Annie Blizard
Jesus Reiné
Carla Solórzano
Edessa Negera
Beatriz Carniel
Alessandra Soares-Schanoski
Victoria Connor
Hugh Adler
Seher R. Zaidi
Caz Hales
Helen Hill
Angie Hyder-Wright
Stephen B. Gordon
Jamie Rylance
Daniela M. Ferreira
author_sort Elissavet Nikolaou
title Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults
title_short Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults
title_full Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults
title_fullStr Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults
title_full_unstemmed Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults
title_sort experimental human challenge defines distinct pneumococcal kinetic profiles and mucosal responses between colonized and non-colonized adults
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/1236366ad73a46a3aea687a3e4c72662
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