Sensitization by pulmonary reactive oxygen species of rat vagal lung C-fibers: the roles of the TRPV1, TRPA1, and P2X receptors.
Sensitization of vagal lung C-fibers (VLCFs) induced by mediators contributes to the pathogenesis of airway hypersensitivity, which is characterized by exaggerated sensory and reflex responses to stimulants. Reactive oxygen species (ROS) are mediators produced during airway inflammation. However, th...
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Main Authors: | Ting Ruan, Yu-Jung Lin, Tien-Huan Hsu, Shing-Hwa Lu, Guey-Mei Jow, Yu Ru Kou |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/123ae6d9133743ffa3dfe46e545538a8 |
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