Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2

Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2

Summary: The rs58542926C >T (E167K) variant of the transmembrane 6 superfamily member 2 gene (TM6SF2) is associated with increased risks for nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). Nevertheless, the role of the TM6SF2 rs58542926 variant in glucose metabolism is poorly...

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Autores principales: Yanbo Fan, Brooke N. Wolford, Haocheng Lu, Wenying Liang, Jinjian Sun, Wei Zhou, Oren Rom, Anubha Mahajan, Ida Surakka, Sarah E. Graham, Zhipeng Liu, Hyunbae Kim, Shweta Ramdas, Lars G. Fritsche, Jonas B. Nielsen, Maiken Elvestad Gabrielsen, Kristian Hveem, Dongshan Yang, Jun Song, Minerva T. Garcia-Barrio, Jifeng Zhang, Wanqing Liu, Kezhong Zhang, Cristen J. Willer, Y. Eugene Chen
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Physiology
Molecular physiology
Diabetology
Genomics
Science
Q
Acceso en línea:https://doaj.org/article/123d0eb5291545f598be4e64a51063ec
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