Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestine

Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestine

Small intestine neuroendocrine tumors (SI-NETs) are frequently multifocal and metastatic, but their tumourigenesis is still poorly understood. Here, the authors analyse multifocal SI-NET tumours with whole-genome sequencing, revealing the landscape of genomic alterations and frequent polyclonal orig...

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Autores principales: Erik Elias, Arman Ardalan, Markus Lindberg, Susanne E. Reinsbach, Andreas Muth, Ola Nilsson, Yvonne Arvidsson, Erik Larsson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/123fb58011ff4c5299d20a2fa8383e2b
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