Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway

Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway

Abstract Andrographolide derivatives or analogs exhibit potent anti-inflammatory effects in several disease models through NF-κB activity. In this study, we synthesized different andrographolide derivatives and investigated their effects on the toll-like receptor (TLR)-induced production of pro-infl...

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Autores principales: Xin Nie, Shao-Ru Chen, Kun Wang, Yuran Peng, Yi-Tao Wang, Decai Wang, Ying Wang, Guo-Chun Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/124559caff544f75908efbc0ce914048
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