Matrix metalloproteinases regulate the formation of dendritic spine head protrusions during chemically induced long-term potentiation.

Dendritic spines are are small membranous protrusions that extend from neuronal dendrites and harbor the majority of excitatory synapses. Increasing evidence has shown that matrix metalloproteinases (MMPs), a family of extracellularly acting and Zn(2+)-dependent endopeptidases, are able to rapidly m...

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Main Authors: Zsuzsanna Szepesi, Monika Bijata, Blazej Ruszczycki, Leszek Kaczmarek, Jakub Wlodarczyk
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
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Online Access:https://doaj.org/article/124584fff00445a1ae018bddc5e4e3f3
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