Developmental adaptation of central nervous system to extremely high acetylcholine levels.
Acetylcholinesterase (AChE) is a key enzyme in termination of fast cholinergic transmission. In brain, acetylcholine (ACh) is produced by cholinergic neurons and released in extracellular space where it is cleaved by AChE anchored by protein PRiMA. Recently, we showed that the lack of AChE in brain...
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Main Authors: | Vladimir Farar, Anna Hrabovska, Eric Krejci, Jaromir Myslivecek |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/12516a657e744683b0867fdeaeca8bd6 |
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