Time-dependent assessment of stimulus-evoked regional dopamine release

It has proven difficult to measure the release of neurotransmitters, such as dopamine, in the human brain. Here, the authors introduce and validate a new method that infers dopamine release based on minute-by-minute fluctuations of the positron emission tomography (PET) radioligand [11C]raclopride.

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Detalles Bibliográficos
Autores principales: Rachel N. Lippert, Anna Lena Cremer, Sharmili Edwin Thanarajah, Clio Korn, Thomas Jahans-Price, Lauren M. Burgeno, Marc Tittgemeyer, Jens C. Brüning, Mark E. Walton, Heiko Backes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1253beac4928441f8de3769b0a67d7d4
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Sumario:It has proven difficult to measure the release of neurotransmitters, such as dopamine, in the human brain. Here, the authors introduce and validate a new method that infers dopamine release based on minute-by-minute fluctuations of the positron emission tomography (PET) radioligand [11C]raclopride.