Time-dependent assessment of stimulus-evoked regional dopamine release

It has proven difficult to measure the release of neurotransmitters, such as dopamine, in the human brain. Here, the authors introduce and validate a new method that infers dopamine release based on minute-by-minute fluctuations of the positron emission tomography (PET) radioligand [11C]raclopride.

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Autores principales:	Rachel N. Lippert, Anna Lena Cremer, Sharmili Edwin Thanarajah, Clio Korn, Thomas Jahans-Price, Lauren M. Burgeno, Marc Tittgemeyer, Jens C. Brüning, Mark E. Walton, Heiko Backes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1253beac4928441f8de3769b0a67d7d4
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spelling	oai:doaj.org-article:1253beac4928441f8de3769b0a67d7d42021-12-02T14:39:40ZTime-dependent assessment of stimulus-evoked regional dopamine release10.1038/s41467-018-08143-42041-1723https://doaj.org/article/1253beac4928441f8de3769b0a67d7d42019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08143-4https://doaj.org/toc/2041-1723It has proven difficult to measure the release of neurotransmitters, such as dopamine, in the human brain. Here, the authors introduce and validate a new method that infers dopamine release based on minute-by-minute fluctuations of the positron emission tomography (PET) radioligand [11C]raclopride.Rachel N. LippertAnna Lena CremerSharmili Edwin ThanarajahClio KornThomas Jahans-PriceLauren M. BurgenoMarc TittgemeyerJens C. BrüningMark E. WaltonHeiko BackesNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rachel N. Lippert Anna Lena Cremer Sharmili Edwin Thanarajah Clio Korn Thomas Jahans-Price Lauren M. Burgeno Marc Tittgemeyer Jens C. Brüning Mark E. Walton Heiko Backes Time-dependent assessment of stimulus-evoked regional dopamine release
description	It has proven difficult to measure the release of neurotransmitters, such as dopamine, in the human brain. Here, the authors introduce and validate a new method that infers dopamine release based on minute-by-minute fluctuations of the positron emission tomography (PET) radioligand [11C]raclopride.
format	article
author	Rachel N. Lippert Anna Lena Cremer Sharmili Edwin Thanarajah Clio Korn Thomas Jahans-Price Lauren M. Burgeno Marc Tittgemeyer Jens C. Brüning Mark E. Walton Heiko Backes
author_facet	Rachel N. Lippert Anna Lena Cremer Sharmili Edwin Thanarajah Clio Korn Thomas Jahans-Price Lauren M. Burgeno Marc Tittgemeyer Jens C. Brüning Mark E. Walton Heiko Backes
author_sort	Rachel N. Lippert
title	Time-dependent assessment of stimulus-evoked regional dopamine release
title_short	Time-dependent assessment of stimulus-evoked regional dopamine release
title_full	Time-dependent assessment of stimulus-evoked regional dopamine release
title_fullStr	Time-dependent assessment of stimulus-evoked regional dopamine release
title_full_unstemmed	Time-dependent assessment of stimulus-evoked regional dopamine release
title_sort	time-dependent assessment of stimulus-evoked regional dopamine release
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1253beac4928441f8de3769b0a67d7d4
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Time-dependent assessment of stimulus-evoked regional dopamine release

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