In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin

ABSTRACT Simian virus 40 VP4 was discovered in 2007 as a later expressed viral protein initiated from a downstream Met on the VP2/VP3 transcript. VP4’s role as a viroporin involved in viral release was supported in a series of additional articles that characterized the ability of VP4 to associate wi...

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Autores principales: Robert Daniels, Daniel N. Hebert
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Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/12556a81129943ae9aecf09feb1fff6e
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spelling oai:doaj.org-article:12556a81129943ae9aecf09feb1fff6e2021-11-15T15:29:17ZIn Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin10.1128/mSphere.00187-202379-5042https://doaj.org/article/12556a81129943ae9aecf09feb1fff6e2020-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00187-20https://doaj.org/toc/2379-5042ABSTRACT Simian virus 40 VP4 was discovered in 2007 as a later expressed viral protein initiated from a downstream Met on the VP2/VP3 transcript. VP4’s role as a viroporin involved in viral release was supported in a series of additional articles that characterized the ability of VP4 to associate with and permeabilize biological membranes. This commentary is our response to the perspective from Henriksen and Rinaldo (mSphere 5:e00019-20, 2020, https://doi.org/10.1128/mSphere.00019-20) that challenges the existence of SV40 VP4.Robert DanielsDaniel N. HebertAmerican Society for Microbiologyarticlenonenveloped virussimian virus 40viral releaseviroporinMicrobiologyQR1-502ENmSphere, Vol 5, Iss 2 (2020)
institution DOAJ
collection DOAJ
language EN
topic nonenveloped virus
simian virus 40
viral release
viroporin
Microbiology
QR1-502
spellingShingle nonenveloped virus
simian virus 40
viral release
viroporin
Microbiology
QR1-502
Robert Daniels
Daniel N. Hebert
In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
description ABSTRACT Simian virus 40 VP4 was discovered in 2007 as a later expressed viral protein initiated from a downstream Met on the VP2/VP3 transcript. VP4’s role as a viroporin involved in viral release was supported in a series of additional articles that characterized the ability of VP4 to associate with and permeabilize biological membranes. This commentary is our response to the perspective from Henriksen and Rinaldo (mSphere 5:e00019-20, 2020, https://doi.org/10.1128/mSphere.00019-20) that challenges the existence of SV40 VP4.
format article
author Robert Daniels
Daniel N. Hebert
author_facet Robert Daniels
Daniel N. Hebert
author_sort Robert Daniels
title In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_short In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_full In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_fullStr In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_full_unstemmed In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
title_sort in support of simian polyomavirus 40 vp4 as a later expressed viroporin
publisher American Society for Microbiology
publishDate 2020
url https://doaj.org/article/12556a81129943ae9aecf09feb1fff6e
work_keys_str_mv AT robertdaniels insupportofsimianpolyomavirus40vp4asalaterexpressedviroporin
AT danielnhebert insupportofsimianpolyomavirus40vp4asalaterexpressedviroporin
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