Rapid generation of microRNA sponges for microRNA inhibition.

Rapid generation of microRNA sponges for microRNA inhibition.

MicroRNA (miRNA) sponges are transcripts with repeated miRNA antisense sequences that can sequester miRNAs from endogenous targets. MiRNA sponges are valuable tools for miRNA loss-of-function studies both in vitro and in vivo. We developed a fast and flexible method to generate miRNA sponges and tes...

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Autores principales: Joost Kluiver, Johan H Gibcus, Chris Hettinga, Annelies Adema, Mareike K S Richter, Nancy Halsema, Izabella Slezak-Prochazka, Ye Ding, Bart-Jan Kroesen, Anke van den Berg
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1256f1c9cefc4fd5b38bc1b72552081e
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