Large cell morphology, CMYC+ tumour cells, and PD-1+ tumour cell/intense PD-L1+ cell reactions are important prognostic factors in nodal peripheral T-cell lymphomas with T follicular helper markers

Large cell morphology, CMYC+ tumour cells, and PD-1+ tumour cell/intense PD-L1+ cell reactions are important prognostic factors in nodal peripheral T-cell lymphomas with T follicular helper markers

Abstract Background The clinicopathological characteristics and prognostic factors in nodal peripheral T-cell lymphomas (PTCLs) with two or more T follicular helper markers (TFH+) are not adequately investigated. Methods Immunohistologically, we selected 22 patients with TFH+ lymphoma (PTCL-TFH) in...

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Bibliographic Details
Main Authors: Yasuhito Mihashi, Shoichi Kimura, Hiromi Iwasaki, Yumi Oshiro, Yasushi Takamatsu, Shigeto Kawauchi, Shohei Shimajiri, Kenji Ishizuka, Morishige Takeshita
Format: article
Language:EN
Published: BMC 2021
Subjects:
AITL
CMYC
PD-1
PD-L1
Peripheral T-cell lymphoma
T follicular helper cell
Pathology
RB1-214
Online Access:https://doaj.org/article/125b8136aa08439e9210053c714ac3ac
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