Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2

The Golgi mitotic checkpoint couples Golgi inheritance with cell cycle transition, and regulates centrosomal recruitment of the mitotic kinase Aurora-A. Here the authors show that upon Golgi ribbon fragmentation in G2, Src phosphorylates Aurora-A at the Golgi, driving its localization to the centros...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Maria Luisa Barretta, Daniela Spano, Chiara D’Ambrosio, Romina Ines Cervigni, Andrea Scaloni, Daniela Corda, Antonino Colanzi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1271109cfb3444aaaafedc4090279e85
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1271109cfb3444aaaafedc4090279e85
record_format	dspace
spelling	oai:doaj.org-article:1271109cfb3444aaaafedc4090279e852021-12-02T15:34:32ZAurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G210.1038/ncomms117272041-1723https://doaj.org/article/1271109cfb3444aaaafedc4090279e852016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11727https://doaj.org/toc/2041-1723The Golgi mitotic checkpoint couples Golgi inheritance with cell cycle transition, and regulates centrosomal recruitment of the mitotic kinase Aurora-A. Here the authors show that upon Golgi ribbon fragmentation in G2, Src phosphorylates Aurora-A at the Golgi, driving its localization to the centrosomes.Maria Luisa BarrettaDaniela SpanoChiara D’AmbrosioRomina Ines CervigniAndrea ScaloniDaniela CordaAntonino ColanziNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maria Luisa Barretta Daniela Spano Chiara D’Ambrosio Romina Ines Cervigni Andrea Scaloni Daniela Corda Antonino Colanzi Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2
description	The Golgi mitotic checkpoint couples Golgi inheritance with cell cycle transition, and regulates centrosomal recruitment of the mitotic kinase Aurora-A. Here the authors show that upon Golgi ribbon fragmentation in G2, Src phosphorylates Aurora-A at the Golgi, driving its localization to the centrosomes.
format	article
author	Maria Luisa Barretta Daniela Spano Chiara D’Ambrosio Romina Ines Cervigni Andrea Scaloni Daniela Corda Antonino Colanzi
author_facet	Maria Luisa Barretta Daniela Spano Chiara D’Ambrosio Romina Ines Cervigni Andrea Scaloni Daniela Corda Antonino Colanzi
author_sort	Maria Luisa Barretta
title	Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2
title_short	Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2
title_full	Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2
title_fullStr	Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2
title_full_unstemmed	Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2
title_sort	aurora-a recruitment and centrosomal maturation are regulated by a golgi-activated pool of src during g2
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/1271109cfb3444aaaafedc4090279e85
work_keys_str_mv	AT marialuisabarretta auroraarecruitmentandcentrosomalmaturationareregulatedbyagolgiactivatedpoolofsrcduringg2 AT danielaspano auroraarecruitmentandcentrosomalmaturationareregulatedbyagolgiactivatedpoolofsrcduringg2 AT chiaradambrosio auroraarecruitmentandcentrosomalmaturationareregulatedbyagolgiactivatedpoolofsrcduringg2 AT rominainescervigni auroraarecruitmentandcentrosomalmaturationareregulatedbyagolgiactivatedpoolofsrcduringg2 AT andreascaloni auroraarecruitmentandcentrosomalmaturationareregulatedbyagolgiactivatedpoolofsrcduringg2 AT danielacorda auroraarecruitmentandcentrosomalmaturationareregulatedbyagolgiactivatedpoolofsrcduringg2 AT antoninocolanzi auroraarecruitmentandcentrosomalmaturationareregulatedbyagolgiactivatedpoolofsrcduringg2
_version_	1718386765113327616

Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2

Ejemplares similares