Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2
The Golgi mitotic checkpoint couples Golgi inheritance with cell cycle transition, and regulates centrosomal recruitment of the mitotic kinase Aurora-A. Here the authors show that upon Golgi ribbon fragmentation in G2, Src phosphorylates Aurora-A at the Golgi, driving its localization to the centros...
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Autores principales: | Maria Luisa Barretta, Daniela Spano, Chiara D’Ambrosio, Romina Ines Cervigni, Andrea Scaloni, Daniela Corda, Antonino Colanzi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/1271109cfb3444aaaafedc4090279e85 |
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