Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas

Alena Furdová,1 Miron Sramka,2 Andrej Thurzo,3 Adriana Furdová3 1Department of Ophthalmology, Faculty of Medicine, Comenius University, 2Department of Stereotactic Radiosurgery, St Elisabeth Cancer Inst and St Elisabeth University College of Health and Social Work, 3Department...

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Autores principales: Furdová A, Sramka M, Thurzo A
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Lenguaje:EN
Publicado: Dove Medical Press 2017
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spelling oai:doaj.org-article:1273c3c9b7b44b649ff765f55522bb502021-12-02T02:36:25ZEarly experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas1177-5483https://doaj.org/article/1273c3c9b7b44b649ff765f55522bb502017-01-01T00:00:00Zhttps://www.dovepress.com/early-experiences-of-planning-stereotactic-radiosurgery-using-3d-print-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Alena Furdová,1 Miron Sramka,2 Andrej Thurzo,3 Adriana Furdová3 1Department of Ophthalmology, Faculty of Medicine, Comenius University, 2Department of Stereotactic Radiosurgery, St Elisabeth Cancer Inst and St Elisabeth University College of Health and Social Work, 3Department of Simulation and Virtual Medical Education, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic Objective: The objective of this study was to determine the use of 3D printed model of an eye with intraocular tumor for linear accelerator-based stereotactic radiosurgery.Methods: The software for segmentation (3D Slicer) created virtual 3D model of eye globe with tumorous mass based on tissue density from computed tomography and magnetic resonance imaging data. A virtual model was then processed in the slicing software (Simplify3D®) and printed on 3D printer using fused deposition modeling technology. The material that was used for printing was polylactic acid.Results: In 2015, stereotactic planning scheme was optimized with the help of 3D printed model of the patient’s eye with intraocular tumor. In the period 2001–2015, a group of 150 patients with uveal melanoma (139 choroidal melanoma and 11 ciliary body melanoma) were treated. The median tumor volume was 0.5 cm3 (0.2–1.6 cm3). The radiation dose was 35.0 Gy by 99% of dose volume histogram.Conclusion: The 3D printed model of eye with tumor was helpful in planning the process to achieve the optimal scheme for irradiation which requires high accuracy of defining the targeted tumor mass and critical structures. Keywords: 3D printing, uveal melanoma, stereotactic radiosurgery, linear accelerator, intraocular tumor, stereotactic planning schemeFurdová ASramka MThurzo AFurdová ADove Medical Pressarticle3D printinguveal melanomastereotactic radiosurgerylinear acceleratorOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 267-271 (2017)
institution DOAJ
collection DOAJ
language EN
topic 3D printing
uveal melanoma
stereotactic radiosurgery
linear accelerator
Ophthalmology
RE1-994
spellingShingle 3D printing
uveal melanoma
stereotactic radiosurgery
linear accelerator
Ophthalmology
RE1-994
Furdová A
Sramka M
Thurzo A
Furdová A
Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas
description Alena Furdová,1 Miron Sramka,2 Andrej Thurzo,3 Adriana Furdová3 1Department of Ophthalmology, Faculty of Medicine, Comenius University, 2Department of Stereotactic Radiosurgery, St Elisabeth Cancer Inst and St Elisabeth University College of Health and Social Work, 3Department of Simulation and Virtual Medical Education, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic Objective: The objective of this study was to determine the use of 3D printed model of an eye with intraocular tumor for linear accelerator-based stereotactic radiosurgery.Methods: The software for segmentation (3D Slicer) created virtual 3D model of eye globe with tumorous mass based on tissue density from computed tomography and magnetic resonance imaging data. A virtual model was then processed in the slicing software (Simplify3D®) and printed on 3D printer using fused deposition modeling technology. The material that was used for printing was polylactic acid.Results: In 2015, stereotactic planning scheme was optimized with the help of 3D printed model of the patient’s eye with intraocular tumor. In the period 2001–2015, a group of 150 patients with uveal melanoma (139 choroidal melanoma and 11 ciliary body melanoma) were treated. The median tumor volume was 0.5 cm3 (0.2–1.6 cm3). The radiation dose was 35.0 Gy by 99% of dose volume histogram.Conclusion: The 3D printed model of eye with tumor was helpful in planning the process to achieve the optimal scheme for irradiation which requires high accuracy of defining the targeted tumor mass and critical structures. Keywords: 3D printing, uveal melanoma, stereotactic radiosurgery, linear accelerator, intraocular tumor, stereotactic planning scheme
format article
author Furdová A
Sramka M
Thurzo A
Furdová A
author_facet Furdová A
Sramka M
Thurzo A
Furdová A
author_sort Furdová A
title Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas
title_short Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas
title_full Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas
title_fullStr Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas
title_full_unstemmed Early experiences of planning stereotactic radiosurgery using 3D printed models of eyes with uveal melanomas
title_sort early experiences of planning stereotactic radiosurgery using 3d printed models of eyes with uveal melanomas
publisher Dove Medical Press
publishDate 2017
url https://doaj.org/article/1273c3c9b7b44b649ff765f55522bb50
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AT thurzoa earlyexperiencesofplanningstereotacticradiosurgeryusing3dprintedmodelsofeyeswithuvealmelanomas
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