Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania

Introduction: Hemangiomas arise from the proliferation of endothelial cells surrounding blood-filled cavities. They have a slightly higher female predilection and about 60–70% of them occur in the head and neck region. Various medical and surgical options are available for the treatment of hemangiom...

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Autores principales:	Mungia Abbas M., Owibingire Sira Stanslaus, Moshy Jeremiah Robert, Sohal Karpal Singh, Sianga William
Formato:	article
Lenguaje:	EN
Publicado:	EDP Sciences 2021
Materias:	hemangioma bleomycin head and neck tanzania Dentistry RK1-715 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/1274a38910cc44dba1e9fb73e54b00c0
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spelling	oai:doaj.org-article:1274a38910cc44dba1e9fb73e54b00c02021-11-08T15:20:51ZPattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania2608-132610.1051/mbcb/2021022https://doaj.org/article/1274a38910cc44dba1e9fb73e54b00c02021-01-01T00:00:00Zhttps://www.jomos.org/articles/mbcb/full_html/2021/04/mbcb200203/mbcb200203.htmlhttps://doaj.org/toc/2608-1326Introduction: Hemangiomas arise from the proliferation of endothelial cells surrounding blood-filled cavities. They have a slightly higher female predilection and about 60–70% of them occur in the head and neck region. Various medical and surgical options are available for the treatment of hemangiomas. Aim: To determine the pattern and management outcomes of head and neck hemangiomas in Tanzania. Material and methods: This was a one-year prospective, cross-sectional study that involved all consecutive patients with head and neck hemangiomas treated in Muhimbili National Hospital. A structured questionnaire was used to collect information including age and sex of the patient, chief complaint and, duration, size and site of the lesion. The treatment modalities were surgery and/or intralesional bleomycin injection (IL-Bleo). A standard dose of bleomycin was 0.3 to 0.6 mg/kg per injection not exceeding 15 units per cycle with a maximum of 6 cycles. Frequency distribution and cross-tabulation were performed and association between variables was assessed by the Chi-square test, whereby the p-value was set at p < 0.05. Results: A total of 58 patients were included in the study. The male to female ratio was 1:1.4 and the median age was 6.15 years. Majority (74%) of the patients had infantile hemangioma. The most common presenting complaint of patients/guardians of the patients were facial disfigurement (94.8%), pain (32.8%) and ulceration (22.4%). The most frequently involved sites were the lips (55.2%) followed by the cheeks (37.9%). In patient who were managed surgically, there was a 100% reduction in size of the lesion. Of those who were treated with bleomycin, the percentage reduction in the area of the lesion ranged from 8.33% to 100% with mean of 72.6%. Only 6% of the patient had post IL-Bleo complications. Conclusion: Head and Neck hemangiomas are more common in females and majority are infantile hemangioma. Facial disfigurement is the commonest presenting complication of these lesions, and the lips and the cheeks are mostly affected areas. Intralesional bleomycin is an effective treatment modality which has low complication rates.Mungia Abbas M.Owibingire Sira StanslausMoshy Jeremiah RobertSohal Karpal SinghSianga WilliamEDP Sciencesarticlehemangiomableomycinhead and necktanzaniaDentistryRK1-715SurgeryRD1-811ENJournal of Oral Medicine and Oral Surgery, Vol 27, Iss 4, p 53 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	hemangioma bleomycin head and neck tanzania Dentistry RK1-715 Surgery RD1-811
spellingShingle	hemangioma bleomycin head and neck tanzania Dentistry RK1-715 Surgery RD1-811 Mungia Abbas M. Owibingire Sira Stanslaus Moshy Jeremiah Robert Sohal Karpal Singh Sianga William Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania
description	Introduction: Hemangiomas arise from the proliferation of endothelial cells surrounding blood-filled cavities. They have a slightly higher female predilection and about 60–70% of them occur in the head and neck region. Various medical and surgical options are available for the treatment of hemangiomas. Aim: To determine the pattern and management outcomes of head and neck hemangiomas in Tanzania. Material and methods: This was a one-year prospective, cross-sectional study that involved all consecutive patients with head and neck hemangiomas treated in Muhimbili National Hospital. A structured questionnaire was used to collect information including age and sex of the patient, chief complaint and, duration, size and site of the lesion. The treatment modalities were surgery and/or intralesional bleomycin injection (IL-Bleo). A standard dose of bleomycin was 0.3 to 0.6 mg/kg per injection not exceeding 15 units per cycle with a maximum of 6 cycles. Frequency distribution and cross-tabulation were performed and association between variables was assessed by the Chi-square test, whereby the p-value was set at p < 0.05. Results: A total of 58 patients were included in the study. The male to female ratio was 1:1.4 and the median age was 6.15 years. Majority (74%) of the patients had infantile hemangioma. The most common presenting complaint of patients/guardians of the patients were facial disfigurement (94.8%), pain (32.8%) and ulceration (22.4%). The most frequently involved sites were the lips (55.2%) followed by the cheeks (37.9%). In patient who were managed surgically, there was a 100% reduction in size of the lesion. Of those who were treated with bleomycin, the percentage reduction in the area of the lesion ranged from 8.33% to 100% with mean of 72.6%. Only 6% of the patient had post IL-Bleo complications. Conclusion: Head and Neck hemangiomas are more common in females and majority are infantile hemangioma. Facial disfigurement is the commonest presenting complication of these lesions, and the lips and the cheeks are mostly affected areas. Intralesional bleomycin is an effective treatment modality which has low complication rates.
format	article
author	Mungia Abbas M. Owibingire Sira Stanslaus Moshy Jeremiah Robert Sohal Karpal Singh Sianga William
author_facet	Mungia Abbas M. Owibingire Sira Stanslaus Moshy Jeremiah Robert Sohal Karpal Singh Sianga William
author_sort	Mungia Abbas M.
title	Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania
title_short	Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania
title_full	Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania
title_fullStr	Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania
title_full_unstemmed	Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania
title_sort	pattern and management outcomes of head and neck hemangiomas: a prospective study from tanzania
publisher	EDP Sciences
publishDate	2021
url	https://doaj.org/article/1274a38910cc44dba1e9fb73e54b00c0
work_keys_str_mv	AT mungiaabbasm patternandmanagementoutcomesofheadandneckhemangiomasaprospectivestudyfromtanzania AT owibingiresirastanslaus patternandmanagementoutcomesofheadandneckhemangiomasaprospectivestudyfromtanzania AT moshyjeremiahrobert patternandmanagementoutcomesofheadandneckhemangiomasaprospectivestudyfromtanzania AT sohalkarpalsingh patternandmanagementoutcomesofheadandneckhemangiomasaprospectivestudyfromtanzania AT siangawilliam patternandmanagementoutcomesofheadandneckhemangiomasaprospectivestudyfromtanzania
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Pattern and management outcomes of head and neck hemangiomas: a prospective study from Tanzania

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