Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis

Rebecca A Kuennen, Reynell Harder Smith, Thomas F Mauger, Elson CraigDepartment of Ophthalmology, The Ohio State University, Columbus, Ohio, USAPurpose: To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine.Methods: A case of advanced A...

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Autores principales:	Rebecca A Kuennen, Reynell Harder Smith, Thomas F Mauger, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/1289a1a20d5841649b5af4504f0d4f90
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spelling	oai:doaj.org-article:1289a1a20d5841649b5af4504f0d4f902021-12-02T05:09:33ZEnucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis1177-54671177-5483https://doaj.org/article/1289a1a20d5841649b5af4504f0d4f902010-09-01T00:00:00Zhttp://www.dovepress.com/enucleation-following-treatment-with-intravenous-pentamidine-for-acant-a5409https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Rebecca A Kuennen, Reynell Harder Smith, Thomas F Mauger, Elson CraigDepartment of Ophthalmology, The Ohio State University, Columbus, Ohio, USAPurpose: To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine.Methods: A case of advanced Acanthamoeba sclerokeratitis was resistant to conventional therapy and was treated with intravenous pentamidine. The eye was later removed due to incapacitating pain.Results: The eye showed Acanthamoeba organisms within the cornea and evidence of acute and chronic inflammation throughout the remainder of the eye. The patient has survived without orbital recurrence for 2 years.Conclusions: This case demonstrates late inflammation with active Acanthameoba keratitis following systemic pentamidine therapy.Keywords: keratitis, scleritis Rebecca A KuennenReynell Harder SmithThomas F Maugeret alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 1145-1149 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Rebecca A Kuennen Reynell Harder Smith Thomas F Mauger et al Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis
description	Rebecca A Kuennen, Reynell Harder Smith, Thomas F Mauger, Elson CraigDepartment of Ophthalmology, The Ohio State University, Columbus, Ohio, USAPurpose: To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine.Methods: A case of advanced Acanthamoeba sclerokeratitis was resistant to conventional therapy and was treated with intravenous pentamidine. The eye was later removed due to incapacitating pain.Results: The eye showed Acanthamoeba organisms within the cornea and evidence of acute and chronic inflammation throughout the remainder of the eye. The patient has survived without orbital recurrence for 2 years.Conclusions: This case demonstrates late inflammation with active Acanthameoba keratitis following systemic pentamidine therapy.Keywords: keratitis, scleritis
format	article
author	Rebecca A Kuennen Reynell Harder Smith Thomas F Mauger et al
author_facet	Rebecca A Kuennen Reynell Harder Smith Thomas F Mauger et al
author_sort	Rebecca A Kuennen
title	Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis
title_short	Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis
title_full	Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis
title_fullStr	Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis
title_full_unstemmed	Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis
title_sort	enucleation following treatment with intravenous pentamidine for acanthamoeba sclerokeratitis
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/1289a1a20d5841649b5af4504f0d4f90
work_keys_str_mv	AT rebeccaakuennen enucleationfollowingtreatmentwithintravenouspentamidineforacanthamoebasclerokeratitis AT reynellhardersmith enucleationfollowingtreatmentwithintravenouspentamidineforacanthamoebasclerokeratitis AT thomasfmauger enucleationfollowingtreatmentwithintravenouspentamidineforacanthamoebasclerokeratitis AT etal enucleationfollowingtreatmentwithintravenouspentamidineforacanthamoebasclerokeratitis
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Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis

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