Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease

Abstract This study aimed to evaluate the efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease. Twenty-five patients with stage III Kümmell disease who received bone cement-augmented pedicle screw fixation at the First Affiliated Hospital of Guangzhou Uni...

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Autores principales:	Guo-ye Mo, Teng-peng Zhou, Hui-zhi Guo, Yong-xian Li, Yong-chao Tang, Dan-qing Guo, Pei-jie Luo, Dong-xiao Li, Kai Yuan, Ling Mo, Shun-cong Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/128f918ea2784bf68e1b666cec02b500
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spelling	oai:doaj.org-article:128f918ea2784bf68e1b666cec02b5002021-12-02T14:33:57ZLong-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease10.1038/s41598-021-93013-12045-2322https://doaj.org/article/128f918ea2784bf68e1b666cec02b5002021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93013-1https://doaj.org/toc/2045-2322Abstract This study aimed to evaluate the efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease. Twenty-five patients with stage III Kümmell disease who received bone cement-augmented pedicle screw fixation at the First Affiliated Hospital of Guangzhou University of Chinese Medicine between June 2009 and December 2015 were enrolled. All patients were females with a history of osteoporosis. The vertebral Cobb angle (V-Cobb angle), the fixed segment Cobb Angle (S-Cobb angle), pelvic parameters, visual Analogue Scale (VAS) score, and Oswestry Disability Index (ODI) were assessed preoperatively, postoperatively and at the final follow-up. Complications, loosening rate, operation time, and intraoperative bleeding were recorded. The average lumbar vertebral density T-value was − 3.68 ± 0.71 SD, and the average age was 71.84 ± 5.39. The V-Cobb angle, S-Cobb angle, and Sagittal Vertical Axis (SVA) were significantly smaller postoperatively compared to the preoperative values. The VAS and ODI at 1 month after surgery were 3.60 ± 1.00 and 36.04 ± 6.12%, respectively, which were both significantly lower than before surgery (VAS: 8.56 ± 1.04, ODI: 77.80 ± 6.57%). Bone cement-augmented pedicle screw fixation is a safe and effective treatment for stage III Kümmell disease. It can effectively correct kyphosis, restore and maintain sagittal balance, and maintain spinal stability.Guo-ye MoTeng-peng ZhouHui-zhi GuoYong-xian LiYong-chao TangDan-qing GuoPei-jie LuoDong-xiao LiKai YuanLing MoShun-cong ZhangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Guo-ye Mo Teng-peng Zhou Hui-zhi Guo Yong-xian Li Yong-chao Tang Dan-qing Guo Pei-jie Luo Dong-xiao Li Kai Yuan Ling Mo Shun-cong Zhang Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
description	Abstract This study aimed to evaluate the efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease. Twenty-five patients with stage III Kümmell disease who received bone cement-augmented pedicle screw fixation at the First Affiliated Hospital of Guangzhou University of Chinese Medicine between June 2009 and December 2015 were enrolled. All patients were females with a history of osteoporosis. The vertebral Cobb angle (V-Cobb angle), the fixed segment Cobb Angle (S-Cobb angle), pelvic parameters, visual Analogue Scale (VAS) score, and Oswestry Disability Index (ODI) were assessed preoperatively, postoperatively and at the final follow-up. Complications, loosening rate, operation time, and intraoperative bleeding were recorded. The average lumbar vertebral density T-value was − 3.68 ± 0.71 SD, and the average age was 71.84 ± 5.39. The V-Cobb angle, S-Cobb angle, and Sagittal Vertical Axis (SVA) were significantly smaller postoperatively compared to the preoperative values. The VAS and ODI at 1 month after surgery were 3.60 ± 1.00 and 36.04 ± 6.12%, respectively, which were both significantly lower than before surgery (VAS: 8.56 ± 1.04, ODI: 77.80 ± 6.57%). Bone cement-augmented pedicle screw fixation is a safe and effective treatment for stage III Kümmell disease. It can effectively correct kyphosis, restore and maintain sagittal balance, and maintain spinal stability.
format	article
author	Guo-ye Mo Teng-peng Zhou Hui-zhi Guo Yong-xian Li Yong-chao Tang Dan-qing Guo Pei-jie Luo Dong-xiao Li Kai Yuan Ling Mo Shun-cong Zhang
author_facet	Guo-ye Mo Teng-peng Zhou Hui-zhi Guo Yong-xian Li Yong-chao Tang Dan-qing Guo Pei-jie Luo Dong-xiao Li Kai Yuan Ling Mo Shun-cong Zhang
author_sort	Guo-ye Mo
title	Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_short	Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_full	Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_fullStr	Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_full_unstemmed	Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_sort	long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage iii kümmell disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/128f918ea2784bf68e1b666cec02b500
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Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease

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