Spermidine Supplementation Protects the Liver Endothelium from Liver Damage in Mice

Spermidine Supplementation Protects the Liver Endothelium from Liver Damage in Mice

Chronic liver diseases are multifactorial and the need to develop effective therapies is high. Recent studies have shown the potential of ameliorating liver disease progression through protection of the liver endothelium. Polyamine spermidine (SPD) is a caloric restriction mimetic with autophagy-enh...

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Main Authors: Genís Campreciós, Maria Ruart, Aina Anton, Nuria Suárez-Herrera, Carla Montironi, Celia Martínez, Natalia Jiménez, Erica Lafoz, Héctor García-Calderó, Marina Vilaseca, Marta Magaz, Mar Coll, Isabel Graupera, Scott L. Friedman, Joan Carles García-Pagán, Virginia Hernández-Gea
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
autophagy
mitophagy
LSEC
endothelial dysfunction
liver fibrosis
Nutrition. Foods and food supply
TX341-641
Online Access:https://doaj.org/article/1294761bd9f54395846543f08d3de8ef
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https://doaj.org/article/1294761bd9f54395846543f08d3de8ef

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