Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain

Thalamocortical dysrhythmia is a key pathology of chronic pain. Here, the authors propose an analytical pipeline to study dynamic fMRI brain networks and demonstrate that chronic low back pain pathophysiology and clinical pain intensity are associated with distinct thalamocortical network dynamics.

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Autores principales: Yiheng Tu, Zening Fu, Cuiping Mao, Maryam Falahpour, Randy L. Gollub, Joel Park, Georgia Wilson, Vitaly Napadow, Jessica Gerber, Suk-Tak Chan, Robert R. Edwards, Ted J. Kaptchuk, Thomas Liu, Vince Calhoun, Bruce Rosen, Jian Kong
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/12950b10b50549f0afb08979efd453c9
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spelling oai:doaj.org-article:12950b10b50549f0afb08979efd453c92021-12-02T18:49:31ZDistinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain10.1038/s41467-020-17788-z2041-1723https://doaj.org/article/12950b10b50549f0afb08979efd453c92020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17788-zhttps://doaj.org/toc/2041-1723Thalamocortical dysrhythmia is a key pathology of chronic pain. Here, the authors propose an analytical pipeline to study dynamic fMRI brain networks and demonstrate that chronic low back pain pathophysiology and clinical pain intensity are associated with distinct thalamocortical network dynamics.Yiheng TuZening FuCuiping MaoMaryam FalahpourRandy L. GollubJoel ParkGeorgia WilsonVitaly NapadowJessica GerberSuk-Tak ChanRobert R. EdwardsTed J. KaptchukThomas LiuVince CalhounBruce RosenJian KongNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yiheng Tu
Zening Fu
Cuiping Mao
Maryam Falahpour
Randy L. Gollub
Joel Park
Georgia Wilson
Vitaly Napadow
Jessica Gerber
Suk-Tak Chan
Robert R. Edwards
Ted J. Kaptchuk
Thomas Liu
Vince Calhoun
Bruce Rosen
Jian Kong
Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
description Thalamocortical dysrhythmia is a key pathology of chronic pain. Here, the authors propose an analytical pipeline to study dynamic fMRI brain networks and demonstrate that chronic low back pain pathophysiology and clinical pain intensity are associated with distinct thalamocortical network dynamics.
format article
author Yiheng Tu
Zening Fu
Cuiping Mao
Maryam Falahpour
Randy L. Gollub
Joel Park
Georgia Wilson
Vitaly Napadow
Jessica Gerber
Suk-Tak Chan
Robert R. Edwards
Ted J. Kaptchuk
Thomas Liu
Vince Calhoun
Bruce Rosen
Jian Kong
author_facet Yiheng Tu
Zening Fu
Cuiping Mao
Maryam Falahpour
Randy L. Gollub
Joel Park
Georgia Wilson
Vitaly Napadow
Jessica Gerber
Suk-Tak Chan
Robert R. Edwards
Ted J. Kaptchuk
Thomas Liu
Vince Calhoun
Bruce Rosen
Jian Kong
author_sort Yiheng Tu
title Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
title_short Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
title_full Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
title_fullStr Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
title_full_unstemmed Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
title_sort distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/12950b10b50549f0afb08979efd453c9
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