Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy
Proopiomelanocortin is an anti-nociceptive peptide. Here the authors show in a mouse model of diabetes, that this peptide is downregulated, which may contribute to the neuropathic pain like behaviour in these models.
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| Autores principales: | , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/12a337286d664718a2106d167beb41bd |
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| Sumario: | Proopiomelanocortin is an anti-nociceptive peptide. Here the authors show in a mouse model of diabetes, that this peptide is downregulated, which may contribute to the neuropathic pain like behaviour in these models. |
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